Enprostil

Known as: 4,5-Heptadienoic acid, 7-(3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl)-, methyl ester, (1alpha,2beta(1E,3R*),3alpha)-, Enprostil [Chemical/Ingredient] 
A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2010
010203019852010

Papers overview

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2000
2000
We previously reported that intracolonic administration of enprostil, a prostaglandin-E(2) (PGE(2)) analogue, had therapeutic… (More)
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Highly Cited
1997
Highly Cited
1997
We have characterized the rat prostanoid EP1, EP2, EP3alpha and EP4 receptor subtypes cloned from spleen, hepatocyte and/or… (More)
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1995
1995
BACKGROUND/AIMS It has been suggested that the vulnerability of gastric mucosa is increased in patients with cirrhosis as a… (More)
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1991
1991
Transabdominal real-time ultrasonography was used to investigate antroduodenal motility effects of the prostaglandin E2 analogue… (More)
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1989
1989
Prostaglandin E2 (PGE2) has been reported to exert some centrally mediated effects on intestinal motility and secretion and on… (More)
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1986
1986
This study evaluated the efficacy of two dosage levels of enprostil in 129 patients with gastric ulcer disease. Patients with… (More)
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1986
1986
Enprostil's ability to protect human gastric mucosa against aspirin-induced damage was investigated in a controlled study. Damage… (More)
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1986
1986
Data were combined for statistical analysis from four European trials comparing enprostil (35 micrograms twice daily) with… (More)
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1985
1985
Prostaglandins protect against aspirin-induced damage to the gastrointestinal tract. This study tested the ability of enprostil… (More)
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1985
1985
This study was designed to compare the effects of enprostil, a synthetic dehydro-prostaglandin E2, on 24-h intragastric pH and… (More)
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