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Enprostil

Known as: 4,5-Heptadienoic acid, 7-(3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl)-, methyl ester, (1alpha,2beta(1E,3R*),3alpha)-, Enprostil [Chemical/Ingredient] 
A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Anti-Ulcer Agent

Narrower (2)

GardrinRS-84135
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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1995
1995
Enprostil impairs cholesterol and fat absorption.
BACKGROUND Enprostil, a synthetic dehydroprostaglandin E2 structural analogue primarily developed for treatment of gastritis, has… 
1988
1988
Suppression of Postprandial Glucose, Insulin, C-Peptide, and Glucose-Dependent Insulinotropic Peptide (GIP) in Man by Oral Administration of a Prostaglandin Analogue (Enprostil)
Enprostil, a long-acting, orally active dehydroprostaglandin E2 with cytoprotective and gastric antisecretory properties, is a… 
1987
1987
Enprostil and ranitidine in prevention of duodenal ulcer relapse: one year double blind comparative trial.
One hundred and forty two patients with duodenal ulcer who after a short term study had relief of pain and healed ulcers proved… 
1987
1987
Enprostil and cimetidine: comparative efficacy and safety in patients with duodenal ulcer.
The safety and efficacy of enprostil, 35 micrograms twice daily, and of cimetidine, 400 mg twice daily, in the treatment of… 
1987
1987
Enprostil reduces G-cell hyperplasia and hypergastrinemia in duodenal ulcer.
A 42-year-old man with a 26-year history of duodenal ulcer volunteered for a 24-hour intragastric pH monitoring study, at which… 
Highly Cited
1986
Highly Cited
1986
Enprostil and ranitidine in duodenal ulcer healing: double blind comparative trial.
One hundred and eighty patients with endoscopically proved duodenal ulcers were allocated at random to double blind treatment… 
1986
1986
Effect of enprostil, a synthetic prostaglandin E2 on 24 hour intragastric acidity, nocturnal acid and pepsin secretion.
We have studied the effect of a prostaglandin E2 analogue (enprostil), on intragastric acidity, gastric acid and pepsin outputs… 
1986
1986
Reactivity of enprostil stereoisomers in soft elastic gelatin capsules.
Enprostil (methyl 7-[(1R*,2R*,3R*)-3-hydroxy-2-[(E)-(3R*)-3-hydroxy-4-phenoxy-1-butenyl]- 5-oxocyclopentyl]-4,5-heptadienoate), a… 
1986
1986
Synergistic interaction between an H2-receptor antagonist and enprostil on 24-hour intragastric pH, serum gastrin concentration, and tissue immunoperoxidase staining for gastrin, somatostatin, and…
A 56-year-old woman newly diagnosed as having Zollinger-Ellison syndrome due to a metastatic gastrinoma underwent 24-hour… 
1986
1986
Multidimensional column-switching liquid chromatographic method for dissolution testing of enprostil soft elastic gelatin capsules.
Enprostil (methyl 7-[(1 R,2R,3R)-3-hydroxy-2-[(E)-(3R)-3-hydroxy-4- phenoxy-1-butenyl]-5-oxocyclopentyl]-4,5-heptadienoate), an E…