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Endoplasmic Reticulum-Associated Degradation
Known as:
Pathway, ERAD
, Reticulum-Associated Degradation, Endoplasmic
, Degradation, Endoplasmic Reticulum-Associated
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The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with…
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National Institutes of Health
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Related topics
Related topics
8 relations
Endoplasmic Reticulum Stress
Proteolysis
Ubiquitination
aspects of radiation effects
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
HRD1-mediated PTEN degradation promotes cell proliferation and hepatocellular carcinoma progression.
Liu Liu
,
Hua Long
,
+9 authors
Zhenghong Lin
Cellular Signalling
2018
Corpus ID: 49617732
Review
2017
Review
2017
The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation.
G. Preston
,
J. Brodsky
Biochemical Journal
2017
Corpus ID: 46821286
The endoplasmic reticulum (ER) serves as a warehouse for factors that augment and control the biogenesis of nascent proteins…
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Review
2015
Review
2015
Endoplasmic reticulum quality control in cancer: Friend or foe.
Hana Kim
,
Asmita Bhattacharya
,
Ling Qi
Seminars in Cancer Biology
2015
Corpus ID: 6669765
2015
2015
UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP.
Y. Teng
,
K. Rezvani
,
M. De Biasi
Biochemical Pharmacology
2015
Corpus ID: 34882576
Review
2014
Review
2014
Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion
E. Fisher
,
E. Lake
,
R. McLeod
Journal of Biomedical Research
2014
Corpus ID: 10543693
Abstract Apolipoprotein B (apoB) is the main protein component of very low density lipoprotein (VLDL) and is necessary for the…
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2013
2013
A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.
Y. Erzurumlu
,
Fadime Aydin Kose
,
O. Gozen
,
D. Gozuacik
,
E. Toth
,
Petek Ballar
International Journal of Biochemistry and Cell…
2013
Corpus ID: 29882598
Review
2011
Review
2011
The complexities of p97 function in health and disease.
E. Chapman
,
Anastasia N Fry
,
Minjin Kang
Molecular Biosystems
2011
Corpus ID: 66767
p97 is a homohexameric, toroidal machine that harnesses the energy of ATP binding and hydrolysis to effect structural…
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2009
2009
Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein
Arpita Ray-Sinha
,
B. Cross
,
Aleksandr Mironov
,
E. Wiertz
,
S. High
Molecular membrane biology
2009
Corpus ID: 13938905
Abstract The presence of two basic amino acids strategically located within a single spanning transmembrane region has previously…
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2008
2008
Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system.
M. Takahata
,
M. Bohgaki
,
T. Tsukiyama
,
T. Kondo
,
M. Asaka
,
S. Hatakeyama
Molecular Immunology
2008
Corpus ID: 34410579
2008
2008
SEL1L and HRD1 are involved in the degradation of unassembled secretory Ig‐µ chains
M. Cattaneo
,
M. Otsu
,
+4 authors
I. Biunno
Journal of Cellular Physiology
2008
Corpus ID: 305574
When expressed in the absence of light chains, secretory Ig‐µ chains (µs) undergo endoplasmic reticulum associated degradation…
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