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Endoplasmic Reticulum-Associated Degradation

Known as: Pathway, ERAD, Reticulum-Associated Degradation, Endoplasmic, Degradation, Endoplasmic Reticulum-Associated 
The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with… 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
The endoplasmic reticulum (ER) serves as a warehouse for factors that augment and control the biogenesis of nascent proteins… 
Review
2015
Review
2015
Quality control systems in the endoplasmic reticulum (ER) mediated by unfolded protein response (UPR) and endoplasmic reticulum… 
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Review
2014
Review
2014
Abstract Apolipoprotein B (apoB) is the main protein component of very low density lipoprotein (VLDL) and is necessary for the… 
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2013
2013
p97/VCP is a hexameric AAA type ATPase that functions in a variety of cellular processes such as endoplasmic reticulum associated… 
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2012
2012
EDEM1 is a mannosidase-like protein that recruits misfolded glycoproteins from the calnexin/calreticulin folding cycle to… 
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Review
2011
Review
2011
p97 is a homohexameric, toroidal machine that harnesses the energy of ATP binding and hydrolysis to effect structural… 
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2011
2011
BackgroundPeptide: N- glycanase (PNGase) enzyme cleaves oligosaccharides from the misfolded glycoproteins and prepares them for… 
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2009
2009
Abstract The presence of two basic amino acids strategically located within a single spanning transmembrane region has previously… 
2008
2008
When expressed in the absence of light chains, secretory Ig‐µ chains (µs) undergo endoplasmic reticulum associated degradation… 
2008
2008
The 52-kDa form of SSA/Ro protein (Ro52) is one of autoantigens associated with autoimmune disorders such as systemic lupus…