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Endoplasmic Reticulum-Associated Degradation
Known as:
Pathway, ERAD
, Reticulum-Associated Degradation, Endoplasmic
, Degradation, Endoplasmic Reticulum-Associated
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The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with…
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National Institutes of Health
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Related topics
Related topics
8 relations
Endoplasmic Reticulum Stress
Proteolysis
Ubiquitination
aspects of radiation effects
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erad
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Expression of rabies virus glycoprotein in the methylotrophic yeast Pichia pastoris
Safa Ben Azoun
,
Meriem Ben Zakour
,
S. Sghaier
,
H. Kallel
Biotechnology and applied biochemistry
2017
Corpus ID: 26982926
Rabies is a fatal disease that can be prevented by vaccination. Different approaches were investigated to develop novel human…
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2013
2013
Unfolded Protein Response and Activated Degradative Pathways Regulation in GNE Myopathy
Hong-hao Li
,
Qi Chen
,
+6 authors
Chuanzhu Yan
PLoS ONE
2013
Corpus ID: 4059390
Although intracellular beta amyloid (Aβ) accumulation is known as an early upstream event in the degenerative course of UDP-N…
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2013
2013
SEL1L Regulates Adhesion, Proliferation and Secretion of Insulin by Affecting Integrin Signaling
G. Diaferia
,
V. Cirulli
,
I. Biunno
PLoS ONE
2013
Corpus ID: 6502055
SEL1L, a component of the endoplasmic reticulum associated degradation (ERAD) pathway, has been reported to regulate the (i…
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2012
2012
Using a ubiquitin ligase as an unfolded protein sensor.
Adam Mallinger
,
Hsiang M. Wen
,
Geoff Dankle
,
Kevin A. Glenn
Biochemical and Biophysical Research…
2012
Corpus ID: 6780606
Review
2011
Review
2011
The complexities of p97 function in health and disease.
E. Chapman
,
Anastasia N Fry
,
Minjin Kang
Molecular Biosystems
2011
Corpus ID: 66767
p97 is a homohexameric, toroidal machine that harnesses the energy of ATP binding and hydrolysis to effect structural…
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2010
2010
Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation
J. Otero
,
J. Suo
,
C. Gordon
,
E. Chang
Cell Cycle
2010
Corpus ID: 24554666
Int6/eIF3e is implicated in tumorigenesis, but its molecular functions remain unclear. We have studied its fission yeast homolog…
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2009
2009
Genomic consequences of cytochrome P450 2C9 overexpression in human hepatoma cells.
C. Narjoz
,
L. Marisa
,
+4 authors
I. de Waziers
Chemical Research in Toxicology
2009
Corpus ID: 24814869
Cytochrome P450 2C9 (P450 2C9) is one of the most important P450 isoforms in the human liver, as it metabolizes numerous…
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2008
2008
Ro52 functionally interacts with IgG1 and regulates its quality control via the ERAD system.
M. Takahata
,
M. Bohgaki
,
T. Tsukiyama
,
T. Kondo
,
M. Asaka
,
S. Hatakeyama
Molecular Immunology
2008
Corpus ID: 34410579
2008
2008
SEL1L and HRD1 are involved in the degradation of unassembled secretory Ig‐µ chains
M. Cattaneo
,
M. Otsu
,
+4 authors
I. Biunno
Journal of Cellular Physiology
2008
Corpus ID: 305574
When expressed in the absence of light chains, secretory Ig‐µ chains (µs) undergo endoplasmic reticulum associated degradation…
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2007
2007
Tipping the Delicate Balance: Defining How Proteasome Maturation Affects the Degradation of a Substrate for Autophagy and Endoplasmic Reticulum Associated Degradation (ERAD)
J. Brodsky
,
C. Scott
Autophagy
2007
Corpus ID: 29342069
An increasing body of data links endoplasmic reticulum (ER) function to autophagy. Not surprisingly, then, some aberrant proteins…
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