Skip to search formSkip to main contentSkip to account menu

Endoglin, human

Known as: CD105 Antigen, Endoglin (Osler-Rendu-Weber Syndrome 1), ORW 
Endoglin (658 aa, ~71 kDa) is encoded by the human ENG gene. This protein plays a role in transforming growth factor receptor signaling.
National Institutes of Health

Related topics

Related topics

18 relations
Cell Proliferation Regulatory ProcessENG geneENG wt AlleleEndoglin activity

Broader (1)

Endoglin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Characterization of protocols for primary trophoblast purification, optimized for functional investigation of sFlt-1 and soluble endoglin.
Highly Cited
2012
Highly Cited
2012
CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma
Paediatric high grade glioma (pHGG) (World Health Organisation astrocytoma grades III and IV) remains poor prognosis tumours… 
Highly Cited
2011
Highly Cited
2011
Endoglin regulates cancer-stromal cell interactions in prostate tumors.
Endoglin is an accessory receptor for TGF-β that has been implicated in prostate cancer cell detachment, migration, and… 
2008
2008
Endoglin (CD105) and microvessel density in oral squamous cell carcinoma.
Recent studies revealed that CD105 is intensively expressed in tumor vasculature, and may be an important prognostic indicator… 
Highly Cited
2006
Highly Cited
2006
Endoglin regulates renal ischaemia-reperfusion injury.
BACKGROUND Renal ischaemia-reperfusion (I-R) can cause acute tubular necrosis and chronic renal deterioration. Endoglin, an… 
2005
2005
Functional role of CD105 in TGF-beta1 signalling in murine and human endothelial cells.
BACKGROUND Angiogenesis is important in health and several disease states. CD105 is a proliferation-associated and hypoxia… 
Highly Cited
2002
Highly Cited
2002
Contrast echocardiography can assess risk area and infarct size during coronary occlusion and reperfusion: experimental validation.
Highly Cited
2001
Highly Cited
2001
Identification of a Critical Sp1 Site within the Endoglin Promoter and Its Involvement in the Transforming Growth Factor-β Stimulation*
Endoglin, a component of the transforming growth factor-β (TGF-β) receptor complex expressed on endothelial cells, is involved in… 
Highly Cited
2001
Highly Cited
2001
Endoglin expression in human and rat mesangial cells and its upregulation by TGF-beta1.
Endoglin is a component of the TGF-beta receptor complex present in the kidney at the human glomerular mesangium. Since the… 
1998
1998
Endoglin, a component of the TGF‐β receptor system, is a differentiation marker of human choriocarcinoma cells
Endoglin is an integral membrane glycoprotein that binds transforming growth factor‐β1 (TGF‐β1) with high affinity and it is… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)