ENG wt Allele

Known as: CD105 Gene, ORW Gene, Endoglin (Osler-Rendu-Weber Syndrome 1) wt Allele 
Human ENG wild-type allele is located within 9q33-q34.1 and is approximately 40 kb in length. This allele, which encodes endoglin protein, is… (More)
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
Purpose: Hereditary hemorrhagic telangiectasia is an autosomal dominant disorder characterized by arteriovenous malformations… (More)
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Highly Cited
2006
Highly Cited
2006
Hereditary hemorrhagic telangiectasia (HHT) is a genetically heterogeneous vascular dysplasia with multiple telangiectases and… (More)
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Highly Cited
2004
Highly Cited
2004
Mutations in the human endoglin gene result in hereditary hemorrhagic telangiectasia type 1, a vascular disorder characterized by… (More)
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Highly Cited
2003
Highly Cited
2003
CD105 and its ligand transforming growth factor β (TGFβ) are modulators of angiogenesis, which drives tumour growth and… (More)
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Highly Cited
2002
Highly Cited
2002
Hereditary hemorrhagic telangiectasia (HHT or Rendu-Osler-Weber syndrome) is an autosomal dominant disorder characterized by… (More)
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Highly Cited
2000
Highly Cited
2000
Endoglin (CD105) is expressed on the surface of endothelial and haematopoietic cells in mammals and binds TGFbeta isoforms 1 and… (More)
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Highly Cited
2000
Highly Cited
2000
CD105 (endoglin), a receptor for transforming growth factor (TGF) beta1 and beta3 in vascular endothelial cells, is highly up… (More)
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Highly Cited
2000
Highly Cited
2000
ALK-1 (activin receptor-like kinase-1), a type I receptor of the transforming growth factor (TGF)-beta superfamily, is the gene… (More)
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Highly Cited
1999
Highly Cited
1999
Endoglin is a transforming growth factor-beta (TGF-beta) binding protein expressed on the surface of endothelial cells. Loss-of… (More)
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1996
1996
Pulmonary arteriovenous malformations (PAVMs) occur in up to 27% of patients with hereditary haemorrhagic telangiectasia (HHT… (More)
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