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Elongation by Telomerase

Most telomeres are maintained by telomerase. The enzymatic activity of telomerase lengthens terminal regions of eukaryotic telomeric DNA by RNA… 
National Institutes of Health

Related topics

Related topics

8 relations
Cell SurvivalDouble-Strand Break Repair Protein MRE11AMRE11A geneMRE11A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
In Situ Visualization of Telomere Length, Telomere Elongation, and TERT Expression in Single Cells
Telomerase plays a critical role in cancer and aging by adding hexa‐nucleotide repeats to the ends of telomeres and extending the… 
2018
2018
Human RTEL 1 stabilizes long G-overhangs allowing telomerase-dependent overextension
Telomere maintenance protects the cell against genome instability and senescence. Accelerated telomere attrition is a… 
2018
2018
A resonance Rayleigh scattering sensor for sensitive differentiation of telomere DNA length and monitoring special motifs (G-quadruplex and i-motif) based on the Ag nanoclusters and NAND logic gate…
BackgroundDifferentiation of telomere length is of vital importance because telomere length is closely related with several… 
2015
2015
Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis
Review
2013
Review
2013
Beyond Telomerase: Telomere Instability as a Novel Target for Cancer Therapy
Telomeres are areas of heterochromatin composed of TTAGGG repeats located at the ends of linear chromosomes. They play a critical… 
Review
2011
Review
2011
Cell-cycle-dependent telomere elongation by telomerase in budding yeast.
Telomeres are essential for the stability and complete replication of linear chromosomes. Telomere elongation by telomerase… 
Review
2004
Review
2004
Polypeptide Components of Telomere Nucleoprotein Complex
  • A. Kuimov
  • Biochemistry (Moscow)
  • 2004
  • Corpus ID: 20146797
Chromosome telomeres of humans and many model organisms contain a structure called a t-loop, which is maintained by TERF, TINF2… 
2002
2002
Real-Time Determination of Telomerase Activity in Cell Extracts Using an Optical Biosensor
Abstract A biosensoric approach has been developed to determine the activity of telomerase in tumor cell lysates. An optical… 
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