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Edivoxetine

 
National Institutes of Health

Papers overview

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2017
2017
Edivoxetine (LY2216684 HCl), although a chemically stable drug substance, has shown the tendency to degrade in the presence of… Expand
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2016
2016
OBJECTIVE Three studies examined whether edivoxetine (a highly selective norepinephrine reuptake inhibitor) had efficacy as… Expand
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2015
2015
Inhibition of norepinephrine (NE) reuptake into noradrenergic nerves is a common therapeutic target in the central nervous system… Expand
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2015
2015
Norepinephrine, a neurotransmitter in the autonomic sympathetic nervous system, is deaminated by monoamine oxidase to 3,4… Expand
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2014
2014
BACKGROUND This phase 2 study examined the efficacy and tolerability of edivoxetine, a highly selective norepinephrine reuptake… Expand
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2014
2014
OBJECTIVE The purpose of this study was to assess the efficacy and safety of edivoxetine (LY2216684), a selective norepinephrine… Expand
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Review
2013
Review
2013
There are several investigational drugs in development for the treatment of depression. Some of the novel antidepressants in… Expand
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2013
2013
OBJECTIVE The purpose of this study was to assess the clinical outcomes from an open label study of edivoxetine, a selective… Expand
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2013
2013
PurposeTo assess the impact of hepatic or renal impairment on the pharmacokinetics (PK) of edivoxetine.MethodsTwo separate multi… Expand
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2012
2012
OBJECTIVE Edivoxetine (LY2216684) is a selective and potent norepinephrine reuptake inhibitor (NERI). The pharmacokinetics (PK… Expand
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