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ETV4 gene

Known as: ETS VARIANT GENE 4, PEA3, ETV4 
This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.
National Institutes of Health

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Related topics

6 relations
ETV4 protein, humanEWSR1 geneHomo sapiensTranscriptional Regulation

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ETV4 wt Allele

Papers overview

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Highly Cited
2005
Highly Cited
2005
Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis.
It is now becoming clear that matrix metalloproteinases (MMPs) play a key role in tumor development and growth. MMPs are… 
Review
2004
Review
2004
E1AF, an ets-oncogene family transcription factor.
2004
2004
E1AF/PEA3 reduces the invasiveness of SiHa cervical cancer cells by activating serine proteinase inhibitor squamous cell carcinoma antigen.
Highly Cited
2003
Highly Cited
2003
Met Signaling Is Required for Recruitment of Motor Neurons to PEA3-Positive Motor Pools
2003
2003
PEA3 is the second Ets family transcription factor involved in tumor progression in ovarian carcinoma.
PURPOSE The purpose of this study was to analyze the possible correlation between PEA3 mRNA expression and survival in advanced… 
2000
2000
Expression of various matrix proteases and Ets family transcriptional factors in ovarian cancer cell lines: correlation to invasive potential.
OBJECTIVES The aim of our study was to determine the important molecules responsible for the invasive activity of ovarian cancer… 
Highly Cited
1999
Highly Cited
1999
Increased E1AF expression in mouse fibrosarcoma promotes metastasis through induction of MT1-MMP expression
In this study, we investigated the role of E1AF, a member of ets family transcription factor, in the acquisition of metastatic… 
Highly Cited
1997
Highly Cited
1997
Antisense E1AF transfection restrains oral cancer invasion by reducing matrix metalloproteinase activities.
E1AF is a newly identified human ets-family transcription factor. We have reported that E1AF can up-regulate transcription of… 
1997
1997
Activation of the p21(Waf1/Cip1) promoter by the ets oncogene family transcription factor E1AF.
p21(Waf1/Cip1) is one of the key regulatory proteins in cell cycle, terminal differentiation, and apoptosis. Its promoter was… 
1997
1997
Expression of E1AF, an ets-family transcription factor, is correlated with the invasive phenotype of oral squamous cell carcinoma.
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