ESR1 gene

Known as: ESTROGEN RECEPTOR 1, ESR, ER 
This gene is involved in ligand-activated transcriptional activity.
National Institutes of Health

Papers overview

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2015
2015
BACKGROUND Activating mutations in the estrogen receptor 1 (ESR1) gene are acquired on treatment and can drive resistance to… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Genome-wide association studies have identified several common genetic variants associated with breast cancer risk. It… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Bone mineral density influences the risk of osteoporosis later in life and is useful in the evaluation of the risk of… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND A major challenge in cancer chemotherapy has been developing safe and clinically efficacious chemotherapeutic agents… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND BRCA1-mutant breast tumors are typically estrogen receptor alpha (ER alpha) negative, whereas most sporadic tumors… (More)
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Highly Cited
2005
Highly Cited
2005
Stearoyl-CoA desaturase (SCD) has recently been shown to be a critical control point of lipid partitioning and body weight… (More)
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Highly Cited
2005
Highly Cited
2005
Edwardsiella tarda is a Gram-negative enteric bacterium affecting both animals and humans. Recently, a type III secretion system… (More)
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Highly Cited
2003
Highly Cited
2003
The orphan receptor Ad4BP/SF-1 (NR5A1) is a constitutive activator, and its activity is repressed by another orphan receptor, Dax… (More)
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Highly Cited
2001
Highly Cited
2001
The transcriptional activity of ERalpha (or NR3A1) after binding of ligand is mediated through synergistic action between… (More)
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1999
1999
In addition to neurotransmitters, hormones, acting through the blood stream, also play a role in behavior. To test the potential… (More)
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