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ERCC4 gene

Known as: xeroderma pigmentosum, complementation group F, EXCISION REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 4, RAD1 
This gene is involved in nucleotide excision repair and is involved in the correction of defective nucleotide excision repair in xeroderma… 
National Institutes of Health

Related topics

Related topics

6 relations
DNA RepairERCC4 protein, humanFANCONI ANEMIA, COMPLEMENTATION GROUP QNucleotide Excision Repair

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ERCC4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Placental promoter methylation of DNA repair genes and prenatal exposure to particulate air pollution: an ENVIRONAGE cohort study.
Review
2015
Review
2015
The ERCC1 and ERCC4 (XPF) genes and gene products.
Highly Cited
2014
Highly Cited
2014
ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency.
The DNA damage response kinase ATR and its effector kinase CHEK1 are required for cancer cells to survive oncogene-induced… 
Highly Cited
2014
Highly Cited
2014
Pharmacogenetics of the DNA repair pathways in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.
Highly Cited
2009
Highly Cited
2009
Five Polymorphisms and Breast Cancer Risk: Results from the Breast Cancer Association Consortium
Previous studies have suggested that minor alleles for ERCC4 rs744154, TNF rs361525, CASP10 rs13010627, PGR rs1042838, and BID… 
Highly Cited
2007
Highly Cited
2007
The role of glutathione in the regulation of nucleotide excision repair during oxidative stress.
Highly Cited
2005
Highly Cited
2005
Interindividual Variation in Nucleotide Excision Repair Genes and Risk of Endometrial Cancer
Exposure to estrogens is a likely cause of endometrial cancer, but the means by which estrogens exert this effect are not… 
Highly Cited
1996
Highly Cited
1996
ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs
ERCC4 is an essential human gene in the nucleotide excision repair (NER) pathway, which is responsible for removing UV-C… 
Highly Cited
1995
Highly Cited
1995
The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1.
Meiotic recombination and DNA repair are mediated by overlapping sets of genes. In the yeast Saccharomyces cerevisiae, many genes… 
Highly Cited
1993
Highly Cited
1993
Co‐correction of the ERCC1, ERCC4 and xeroderma pigmentosum group F DNA repair defects in vitro.
The mammalian ERCC1‐encoded polypeptide is required for nucleotide excision repair of damaged DNA and is homologous to… 
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