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ERAP2 gene

Known as: L-RAP, LRAP, LEUKOCYTE-DERIVED ARGININE AMINOPEPTIDASE 
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Intracellular antigen processing by ERAP2: Molecular mechanism and roles in health and disease.
2018
2018
Allele-specific Alterations in the Peptidome Underlie the Joint Association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy *
Virtually all patients of the rare inflammatory eye disease birdshot chorioretinopathy (BSCR) carry the HLA-A*29:02 allele. BSCR… 
2016
2016
Functional Interaction of the Ankylosing Spondylitis–Associated Endoplasmic Reticulum Aminopeptidase 2 With the HLA–B*27 Peptidome in Human Cells
To determine the influence of endoplasmic reticulum aminopeptidase 2 (ERAP‐2) expression on the HLA–B*27 peptidome in live cells. 
2013
2013
EpCAM associates with endoplasmic reticulum aminopeptidase 2 (ERAP2) in breast cancer cells.
Highly Cited
2011
Highly Cited
2011
Fetal ERAP2 variation is associated with preeclampsia in African Americans in a case-control study
BackgroundPreeclampsia affects 3-8% of pregnancies and is a major cause of maternal and perinatal morbidity and mortality… 
Review
2010
Review
2010
Endoplasmic reticulum aminopeptidases: biology and pathogenic potential
Endoplasmic reticulum aminopeptidase 1 (ERAP1) and the closely related ERAP2 are involved in the final trimming of peptides… 
Highly Cited
2009
Highly Cited
2009
The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations
Preeclampsia is a heritable pregnancy disorder that presents new onset hypertension and proteinuria. We have previously reported… 
Highly Cited
2009
Highly Cited
2009
Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis
Objectives To assess whether there is excess transmission of alleles from the ERAP1 ERAP2 locus in families with ankylosing… 
Highly Cited
2006
Highly Cited
2006
Expression of Endoplasmic Reticulum Aminopeptidases in EBV-B Cell Lines from Healthy Donors and in Leukemia/Lymphoma, Carcinoma, and Melanoma Cell Lines1
Peptide trimming in the endoplasmic reticulum (ER), the final step required for the generation of most HLA class I-binding… 
1990
1990
Biochemical characterization of stable high molecular-weight aggregates of amelogenins formed during porcine enamel development.
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