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EPHX2 gene

Known as: EPHX2, EPOXIDE HYDROLASE 2, CYTOSOLIC, epoxide hydrolase 2 
National Institutes of Health

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Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease
Epoxyeicosatrienoic acids (EETs) are signaling lipids produced by cytochrome P450 epoxygenation of arachidonic acid, which are… 
2018
2018
Association of EPHX2 R287Q Polymorphism with Diabetic Nephropathy in Chinese Type 2 Diabetic Patients
The aim of this study was to investigate the relationship between EPHX2 rs751141 (R287Q polymorphism) and diabetic nephropathy… 
2015
2015
Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice
Acute pancreatitis (AP) is an inflammatory disease, and is one of the most common gastrointestinal disorders worldwide. Soluble… 
2013
2013
Altered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injury.
Highly Cited
2012
Highly Cited
2012
Attenuation of Cisplatin-Induced Renal Injury by Inhibition of Soluble Epoxide Hydrolase Involves Nuclear Factor κB Signaling
Acute kidney injury is associated with a significant inflammatory response that has been the target of renoprotection strategies… 
2012
2012
Mechanism of the sex difference in neuronal ischemic cell death
Highly Cited
2008
Highly Cited
2008
Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population
Objective Epoxyeicosatrienoic acids have been recognized for their protective effects on the cardiovascular system. This study… 
2008
2008
Comparative hepatic gene expression profiling of rats treated with 1H,1H,2H,2H-heptadecafluorodecan-1-ol or with pentadecafluorooctanoic acid.
Pentadecafluorooctanoic acid is an established peroxisome proliferator. Little is known about effects of treatment with 1H,1H,2H… 
2008
2008
Altered Soluble Epoxide Hydrolase Gene Expression and Function and Vascular Disease Risk in the Stroke-Prone Spontaneously Hypertensive Rat
Soluble epoxide hydrolase (sEH) metabolizes epoxyeicosatrienoic acids and represents a novel therapeutic target in cardiovascular… 
2005
2005
Differential renal gene expression in prehypertensive and hypertensive spontaneously hypertensive rats.
Development of hypertension stems from both environmental and genetic factors wherein the kidney plays a central role… 
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