ENPP2 gene

Known as: AUTOTAXIN, Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 Gene, ATX 
This gene plays a role in the hydrolysis of lysophospholipids.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
UNLABELLED Pruritus is a seriously disabling symptom accompanying many cholestatic liver disorders. Recent experimental evidence… (More)
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Highly Cited
2011
Highly Cited
2011
Lysophosphatidic acid (LPA), produced extracellularly by autotaxin (ATX), has diverse biological activities implicated in tumor… (More)
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Review
2010
Review
2010
Lysophosphatidic acid (LPA) is a potent lipid mediator that acts on a series of specific G protein-coupled receptors, leading to… (More)
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2010
2010
Lysophosphatidic acid (LPA) is a potent lipid mediator with a wide variety of biological actions mediated through G protein… (More)
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES Recent accumulating evidence indicates that lysophosphatidic acid (LPA) is a lipid mediator, abundantly present in… (More)
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Highly Cited
2006
Highly Cited
2006
Autotaxin (ATX), or nucleotide pyrophosphatase-phosphodiesterase 2, is a secreted lysophospholipase D that promotes cell… (More)
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Highly Cited
2005
Highly Cited
2005
The invasive phenotype of glioblastoma multiforme (GBM) is a hallmark of malignant process, yet molecular mechanisms that dictate… (More)
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Highly Cited
2002
Highly Cited
2002
Autotaxin (ATX) is a tumor cell motility-stimulating factor, originally isolated from melanoma cell supernatants. ATX had been… (More)
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1996
1996
We report the first correlation of Nm23 sequence and its tumor metastasis-suppressive capacity using site-directed mutagenesis… (More)
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Highly Cited
1992
Highly Cited
1992
Autotaxin (ATX) is a potent human motility-stimulating protein that has been identified in the conditioned medium from A2058… (More)
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