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ENL Protein

Known as: YEATS Domain-Containing Protein 1, Trithorax Homolog 1, MLLT1 
Protein ENL (559 aa, ~62 kDa) is encoded by the human MLLT1 gene. This protein is involved in transcription.
National Institutes of Health

Related topics

Related topics

6 relations
Chromatin Remodeling FactorGenes, RegulatorMLLT1 geneMLLT1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Initiation of MLL-rearranged AML is dependent on C/EBPα
C/EBPα collaborates with MLL-ENL to activate a group of genes that, together with Hoxa9 and Meis1, are responsible for the early… 
Highly Cited
1999
Highly Cited
1999
The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator
Translocations affecting the chromosomal locus 11q23 are hallmarks of infant leukemias. These events disrupt the MLL gene (also… 
Highly Cited
1999
Highly Cited
1999
Neutrophils isolated from leprosy patients release TNF‐α and exhibit accelerated apoptosis in vitro
This study demonstrated that polymorphonuclear neutrophils (PMN) participate in the acute inflammatory response in leprosy as… 
Highly Cited
1998
Highly Cited
1998
The Oncogenic Capacity of HRX-ENL Requires the Transcriptional Transactivation Activity of ENL and the DNA Binding Motifs of HRX
ABSTRACT The HRX gene (also called MLL,ALL-1, and Htrx) at chromosome band 11q23 is associated with specific subsets of acute… 
Highly Cited
1998
Highly Cited
1998
Lepromatous leprosy patients show T helper 1‐like cytokine profile with differential expression of interleukin‐10 during type 1 and 2 reactions
Some leprosy patients suffer from clinical episodes associated with tissue damage which are designated as Type 1 (reversal… 
Highly Cited
1996
Highly Cited
1996
Nerve function impairment in leprosy at diagnosis and at completion of MDT: a retrospective cohort study of 786 patients in Bangladesh.
This retrospective cohort study includes all new leprosy patients registered for multidrug therapy (MDT) in 1990 at the Danish… 
1993
1993
Indapamide Reduces Hypertensive Left Ventricular Hypertrophy: An International Multicenter Study
The effect of 6 months of treatment with indapamide (IND, 2.5 mg/day) on regression of left ventricular hypertrophy (LVH), an… 
Highly Cited
1991
Highly Cited
1991
Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states.
The possible role of cytokines in leprosy reactions was investigated by analysing the levels of tumour necrosis factor (TNF) and… 
Highly Cited
1984
Highly Cited
1984
Differences in predominant T cell phenotypes and distribution pattern in reactional lesions of tuberculoid and lepromatous leprosy.
The nature and histological pattern of the cutaneous infiltrates of 17 leprosy patients in reversal reactions (Type I) and… 
Highly Cited
1981
Highly Cited
1981
Studies on T cell subsets and functions in leprosy.
T cell subsets and T cell functions were explored in 31 leprosy patients with the following methods: determination of the… 
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