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Natural emergence of antigen-reactive T cells in lepromatous leprosy patients during erythema nodosum leprosum
Significantly, perturbations of T-cell reactivity are detectable in ENL reactions, indicating the natural but transient emergence of antigen-induced T cells in LL. Expand
Vitamin A in the treatment of lichen planus pigmentosus
A peculiar ashy grey pigmentation of the skin, tentatively labelled as lichen planus pigmentosus (LPP), was described by us in 1974 and there is some evidence to suggest that paraphenylenediamine may be playing a role. Expand
Leprosy has been regarded as a host dependent disease that presents an immunological spectrum that shows hyper gammaglobulinemia with significantly elevated levels of IgG and IgA while tuberculoid leprosy patients showed raised IgG levels. Expand
T cell subsets in leprosy lesions: in situ characterization using monoclonal antibodies.
Cryostat sections of dermal lesions from 30 untreated leprosy patients were studied by indirect immunofluorescence using monoclonal antibodies defining T cell subsets and Ia like antigens indicating thereby the presence of activated T cells. Expand
Keratinocyte damage in vitiligo
Light and electron‐microscopic studies were performed on the amelanotic and adjacent normal‐appearing skin in patients with vitiligo, which revealed complete loss of pigment and absence of melanocytes and severe degenerative changes of melanoeyles. Expand
Tinea capitis in North India.
A survey of 1620 school children was undertaken to assess the prevalence of tinea capitis in India, and Trichophyton violaceum was found to be the predominant species followed by T. mentagrophytes. Expand
Reduction of a subpopulation of T lymphocytes in lepromatous leprosy
A reduction innumber ofasubpopulation of lymphocytes was noted in lepromatousleprosy cases with high bacillary load and patients irrespective of treatment and bACillary load. Expand
Evidence for the presence of M. leprae reactive T lymphocytes in patients with lepromatous leprosy.
Addition of exogenous, purified human interleukin-2 (IL-2) to antigen stimulated PBMC from some lepromatous patients showed the best improvement in terms of overall 3H-thymidine incorporation, indicating that leprom atous patients possess T cells which can differentiate to an IL-2 responsive state. Expand
Effect of hair oils and fatty acids on the growth of dermatophytes and their in vitro penetration of human scalp hair.
Various concentrations of commonly used hair oils, unsaturated and saturated fatty acids were incorporated in Sabouraud's dextrose agar medium and their effect on growth of dermatophytes was studied.Expand
Influence of chemotherapy and serum factors on the mitogenic response of peripheral leucocytes of leprosy patients to phytohaemagglutinin.
Mitogenic response to phytohaemagglutinin of peripheral leucocytes from patients with polar forms of leprosy namely lepromatous le Prosy (LL) and tuberculoidLeprosy (TT) has been evaluated and plasma factors were found to be contributory agents to the type of response elicited. Expand