MLLT1 gene

Known as: ENL, Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 1 Gene, LTG19 
This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The Super Elongation Complex (SEC), containing transcription elongation activators/coactivators P-TEFb, ELL2, AFF4/1, ENL, and… (More)
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2011
2011
OBJECTIVE The aim of this study was to better understand how mixed lineage leukemia (MLL) fusion proteins deregulate the… (More)
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2009
2009
PURPOSE Lignans such as secoisolariciresinol diglucoside in flaxseed, are metabolizes to bioactive mammalian lignans of END and… (More)
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2008
2008
Reciprocal chromosomal translocations at the MLL gene locus result in expression of novel fusion proteins, such as MLL-ENL… (More)
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2005
2005
Chromosomal translocations are primary events in tumorigenesis. Those involving the mixed lineage leukaemia (MLL) gene are found… (More)
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Highly Cited
1998
Highly Cited
1998
The HRX gene (also called MLL, ALL-1, and Htrx) at chromosome band 11q23 is associated with specific subsets of acute leukemias… (More)
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Highly Cited
1996
Highly Cited
1996
The SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products are all required for proper transcriptional control of many genes in… (More)
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1994
1994
Chromosome band 11q23 is the site of recurring translocations with a variety of partner chromosomes in myeloid and lymphoid acute… (More)
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Highly Cited
1993
Highly Cited
1993
The MLL gene, on human chromosome 11q23, undergoes chromosomal translocation in acute leukemias, resulting in gene fusion with… (More)
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Highly Cited
1992
Highly Cited
1992
We have identified a human homolog of the Drosophila trithorax protein that is structurally altered by 11q23 translocations in… (More)
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