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ENGASE gene
Known as:
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
, Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase
, ENDO-BETA-N-ACETYLGLUCOSAMINIDASE
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National Institutes of Health
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Related topics
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Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A New Fluorogenic Probe for the Detection of endo‐β‐N‐Acetylglucosaminidase
Nozomi Ishii
,
Chie Sunaga
,
+5 authors
I. Matsuo
ChemBioChem
2018
Corpus ID: 3296912
We developed a fluorescence‐quenching‐based assay system to determine the hydrolysis activity of endo‐β‐N‐acetylglucosaminidases…
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Review
2017
Review
2017
The ENGases: versatile biocatalysts for the production of homogeneous N-linked glycopeptides and glycoproteins.
A. Fairbanks
Chemical Society Reviews
2017
Corpus ID: 206024038
The endo-β-N-acetylglucosaminidases (ENGases) are an enzyme class (EC 3.2.1.96) produced by a range of organisms, ranging from…
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2017
2017
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease.
Yiling Bi
,
M. Might
,
H. Vankayalapati
,
B. Kuberan
Bioorganic & Medicinal Chemistry Letters
2017
Corpus ID: 23066797
2017
2017
The additional deletion of Engase can partially rescue the defects caused by Ngly1 deletion
Haruhiko Fujihira
,
Yuki Negishi-Masahara
,
+6 authors
Tadashi Suzuki
2017
Corpus ID: 90291197
2016
2016
Chemoenzymatic Synthesis of a Phosphorylated Glycoprotein.
P. Priyanka
,
Thomas B. Parsons
,
A. Miller
,
F. Platt
,
A. Fairbanks
Angewandte Chemie
2016
Corpus ID: 33950499
The majority of lysosomal enzymes are targeted to the lysosome by post-translational tagging with N-glycans terminating in…
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2016
2016
Non-lysosomal Degradation of Singly Phosphorylated Oligosaccharides Initiated by the Action of a Cytosolic Endo-β-N-acetylglucosaminidase*
Yoichiro Harada
,
Chengcheng Huang
,
S. Yamaki
,
N. Dohmae
,
Tadashi Suzuki
Journal of Biological Chemistry
2016
Corpus ID: 22591965
Phosphorylated oligosaccharides (POSs) are produced by the degradation of dolichol-linked oligosaccharides (DLOs) by an…
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Highly Cited
2015
Highly Cited
2015
Endo-β-N-acetylglucosaminidase forms N-GlcNAc protein aggregates during ER-associated degradation in Ngly1-defective cells
Chengcheng Huang
,
Yoichiro Harada
,
+7 authors
Tadashi Suzuki
Proceedings of the National Academy of Sciences
2015
Corpus ID: 7943451
Significance In the endoplasmic reticulum (ER), N-glycans on glycoproteins play important roles in dictating the folding status…
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Review
2014
Review
2014
Structural features of free N-glycans occurring in plants and functional features of de-N-glycosylation enzymes, ENGase, and PNGase: the presence of unusual plant complex type N-glycans
M. Maeda
,
Y. Kimura
Frontiers in Plant Science
2014
Corpus ID: 13506226
Free N-glycans (FNGs) are present at micromolar concentrations in plant cells during their differentiation, growth, and…
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2008
2008
Changes in Structural Features of Free N-Glycan and Endoglycosidase Activity during Tomato Fruit Ripening
Kosuke Nakamura
,
M. Inoue
,
T. Yoshiie
,
K. Hosoi
,
Y. Kimura
Bioscience, biotechnology and biochemistry
2008
Corpus ID: 37683259
In developing plants, free N-glycans occur ubiquitously at micromolar concentrations. Such oligosaccharides have been proposed to…
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1996
1996
Regulation of De-N-Glycosylation Enzymes in Germinating Radish Seeds
S. Berger
,
A. Menudier
,
R. Julien
,
Y. Karamanos
Plant Physiology
1996
Corpus ID: 39005793
The activities of the de-N-glycosylation enzymes endo-N-acetyl- [beta]-D-glucosaminidase (ENGase; EC 3.2.1.96) and peptide-N4- (N…
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