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ENGASE gene

Known as: Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase, Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase, ENDO-BETA-N-ACETYLGLUCOSAMINIDASE 
National Institutes of Health

Related topics

Related topics

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Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A New Fluorogenic Probe for the Detection of endo‐β‐N‐Acetylglucosaminidase
We developed a fluorescence‐quenching‐based assay system to determine the hydrolysis activity of endo‐β‐N‐acetylglucosaminidases… Expand
Review
2017
Review
2017
The ENGases: versatile biocatalysts for the production of homogeneous N-linked glycopeptides and glycoproteins.
  • A. Fairbanks
  • Chemical Society reviews
  • 2017
    • Corpus ID: 206024038
The endo-β-N-acetylglucosaminidases (ENGases) are an enzyme class (EC 3.2.1.96) produced by a range of organisms, ranging from… Expand
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2017
2017
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease.
N-Glycanase deficiency, or NGLY1 deficiency, is an extremely rare human genetic disease. N-Glycanase, encoded by the gene NGLY1… Expand
2017
2017
The additional deletion of Engase can partially rescue the defects caused by Ngly1 deletion
2016
2016
Chemoenzymatic Synthesis of a Phosphorylated Glycoprotein.
The majority of lysosomal enzymes are targeted to the lysosome by post-translational tagging with N-glycans terminating in… Expand
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2016
2016
Non-lysosomal Degradation of Singly Phosphorylated Oligosaccharides Initiated by the Action of a Cytosolic Endo-β-N-acetylglucosaminidase*
Phosphorylated oligosaccharides (POSs) are produced by the degradation of dolichol-linked oligosaccharides (DLOs) by an… Expand
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Highly Cited
2015
Highly Cited
2015
Endo-β-N-acetylglucosaminidase forms N-GlcNAc protein aggregates during ER-associated degradation in Ngly1-defective cells
Significance In the endoplasmic reticulum (ER), N-glycans on glycoproteins play important roles in dictating the folding status… Expand
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Review
2014
Review
2014
Structural features of free N-glycans occurring in plants and functional features of de-N-glycosylation enzymes, ENGase, and PNGase: the presence of unusual plant complex type N-glycans
Free N-glycans (FNGs) are present at micromolar concentrations in plant cells during their differentiation, growth, and… Expand
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2008
2008
Changes in Structural Features of Free N-Glycan and Endoglycosidase Activity during Tomato Fruit Ripening
In developing plants, free N-glycans occur ubiquitously at micromolar concentrations. Such oligosaccharides have been proposed to… Expand
1996
1996
Regulation of De-N-Glycosylation Enzymes in Germinating Radish Seeds
The activities of the de-N-glycosylation enzymes endo-N-acetyl- [beta]-D-glucosaminidase (ENGase; EC 3.2.1.96) and peptide-N4- (N… Expand
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