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EM 652

Known as: EM-652 
National Institutes of Health

Related topics

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2 relations
Acolbifene

Broader (1)

ritetronium

Papers overview

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2007
2007
Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor α
Anti-estrogen resistance is a major clinical problem in the treatment of breast cancer. In this study, fluorescence resonance… 
2006
2006
Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells
2004
2004
Selective estrogen receptor modulator regulated proteins in endometrial cancer cells
Highly Cited
2003
Highly Cited
2003
Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.
Estrogen receptor (ER)alpha and -beta interact with a variety of coactivator proteins, most notably members of the steroid… 
2003
2003
The combination of a novel selective estrogen receptor modulator with an estrogen protects the mammary gland and uterus in a rodent model: the future of postmenopausal women's health?
The Women's Health Initiative Study and other reports have created major uncertainty among postmenopausal women and physicians… 
2003
2003
A Novel Pure SERM Achieves Complete Regression of the Majority of Human Breast Cancer Tumors in Nude Mice
AbstractBackground. The objective was to determine if EM-652, a novel selective estrogen receptor modulator (SERM) having highly… 
2002
2002
Comparison of the effects of EM‐652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW‐5638 and raloxifene on the growth of human ZR‐75‐1 breast tumors in nude mice
EM‐652 exerts pure antiestrogenic activity in the mammary gland and endometrium, while tamoxifen, the antiestrogen most widely… 
2002
2002
Inhibition of low-density lipoprotein oxidation by the pure antiestrogens ICI 182780 and EM-652 (SCH 57068)
ObjectiveThe use of modulators of estrogen receptors activation is receiving increasing interest in menopausal medicine. Pure… 
Review
2001
Review
2001
EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium
1998
1998
EM-800, a novel antiestrogen, acts as a pure antagonist of the transcriptional functions of estrogen receptors alpha and beta.
Estrogens act as potent mitogens in a large number of breast cancers, and the use of estrogen receptor (ER) antagonists is… 
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