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Acolbifene

Known as: (2S)-3-(4-Hydroxyphenyl)-4-methyl-2-(4-(2-(1-piperidinyl)ethoxy)phenyl)-2H-1-benzopyran-7-ol 
National Institutes of Health

Related topics

Related topics

4 relations
Acolbifene HydrochlorideEM 652

Narrower (1)

SCH 57068

Broader (1)

ritetronium

Papers overview

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2015
2015
Clinical Trial of Acolbifene in Premenopausal Women at High Risk for Breast Cancer
The purpose of this study was to assess the feasibility of using the selective estrogen receptor modulator (SERM) acolbifene as a… 
2012
2012
Emerging Selective Estrogen Receptor Modulators
Menopause, regardless of age at onset, is associated with a marked increase in coronary heart disease (CHD) risk. On the basis of… 
2012
2012
Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland
Novel agents for the endocrine therapy of breast cancer are needed, especially in order to take advantage of the multiple… 
2010
2010
Effect of toremifene and ospemifene, compared to acolbifene, on estrogen-sensitive parameters in rat and human uterine tissues
Abstract Background: Although the first generation selective estrogen receptor modulator (SERM) tamoxifen (TAM) is well known for… 
2008
2008
Effects of selective oestrogen receptor modulators on proliferation in tissue cultures of pre- and postmenopausal human endometrium
2006
2006
Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells
Review
2006
Review
2006
Emerging selective estrogen receptor modulators: special focus on effects on coronary heart disease in postmenopausal women.
Menopause, regardless of age at onset, is associated with a marked increase in coronary heart disease (CHD) risk. On the basis of… 
2005
2005
Estrogen receptor α-mediated adiposity-lowering and hypocholesterolemic actions of the selective estrogen receptor modulator acolbifene
OBJECTIVE:The selective estrogen receptor (ER) modulator (SERM) acolbifene (ACOL), a potent and pure antiestrogen in the mammary… 
2005
2005
Synthesis and structure–activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution
EM-652 (acolbifene) analogs have been synthesized as selective estrogen receptor modulators. Substitution on the nitrogen atom of… 
2004
2004
Selective estrogen receptor modulator regulated proteins in endometrial cancer cells
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