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EM 523

Known as: EM-523, EM523L, Erythromycin, 8,9-didehydro-9-deoxo-6-deoxy-6,9-epoxy- 
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Tachyphylaxis may have contributed to the failure of the motilide ABT-229 [N-ethyl, N-methyl 4′′ deoxy erythromycin (EM)-B… Expand
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2005
2005
We investigated the effect of an erythromycin derivative, EM523L, on interdigestive gastrointestinal motor activity and plasma… Expand
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1997
1997
OBJECTIVE To evaluate the effect of the erythromycin derivative EM523L on gastric emptying and postprandial insulin requirement… Expand
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1996
1996
We investigated the efficacy and the mechanism of action of EM523L, a nonpeptide motilin agonist (motilide), on the stimulation… Expand
1996
1996
Motilin was isolated from acid extracts of the small intestine of chickens by a combination of gel filtration chromatography, ion… Expand
1994
1994
EM523L, a newly developed erythromycin derivative, has a powerful motilin-like biologic effect and no antibacterial activity. In… Expand
Highly Cited
1991
Highly Cited
1991
Binding studies with iodinated motilin revealed that in the small intestine motilin receptor density decreased aborally… Expand
Highly Cited
1990
Highly Cited
1990
Erythromycin may stimulate gastrointestinal motor activity via its effect upon motilin receptors. We have studied the ability of… Expand
1990
1990
The effect of EM-523 [de(N-methyl)-N-ethyl-8,9-anhydroerythromycin A 6,9-hemiacetal], an erythromycin derivative, on preparations… Expand
Highly Cited
1989
Highly Cited
1989
The effect of an erythromycin derivative, EM-523, on gastrointestinal motility was investigated in conscious dogs and compared… Expand