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EIF5A gene

Known as: Eukaryotic Translation Initiation Factor 5A Gene, EIF-5A, EIF5A1 
This gene plays a role in mRNA elongation and apoptosis.
National Institutes of Health

Related topics

Related topics

5 relations
ApoptosisGenetic Translation ProcessTranslational Regulationeukaryotic translation initiation factor 5A

Narrower (1)

EIF5A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence
Review
2015
Review
2015
Modulation of protein synthesis by polyamines
Polyamines are ubiquitous small basic molecules that play important roles in cell growth and viability. Since polyamines mainly… 
Highly Cited
2014
Highly Cited
2014
Genome-Wide Analyses and Functional Classification of Proline Repeat-Rich Proteins: Potential Role of eIF5A in Eukaryotic Evolution
The eukaryotic translation factor, eIF5A has been recently reported as a sequence-specific elongation factor that facilitates… 
Review
2010
Review
2010
Modulation of cellular function by polyamines.
Highly Cited
2010
Highly Cited
2010
eIF5A Promotes Translation Elongation, Polysome Disassembly and Stress Granule Assembly
Stress granules (SGs) are cytoplasmic foci at which untranslated mRNAs accumulate in cells exposed to environmental stress. We… 
Highly Cited
2008
Highly Cited
2008
Global Analysis of Gel Mobility of Proteins and Its Use in Target Identification*
SDS-PAGE is a basic method that has long been used for separation of proteins according to their molecular sizes. Despite its… 
Review
2007
Review
2007
Is there a role for eIF5A in translation?
Summary.The putative translation factor eIF5A is essential for cell viability and is highly conserved from archaebacteria to… 
Highly Cited
2006
Highly Cited
2006
eIF5A binds to translational machinery components and affects translation in yeast.
Highly Cited
2005
Highly Cited
2005
Independent roles of eIF5A and polyamines in cell proliferation.
To examine the roles of active hypusinated eIF5A (eukaryotic translation initiation factor 5A) and polyamines in cell… 
Highly Cited
1996
Highly Cited
1996
Inhibition of HIV-1 Replication in Lymphocytes by Mutants of the Rev Cofactor eIF-5A
Eukaryotic initiation factor 5A (eIF-5A) is a cellular cofactor required for the function of the human immunodeficiency virus… 
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