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EIF5A gene

Known as: Eukaryotic Translation Initiation Factor 5A Gene, EIF-5A, EIF5A1 
This gene plays a role in mRNA elongation and apoptosis.
National Institutes of Health

Related topics

Related topics

5 relations
ApoptosisGenetic Translation ProcessTranslational Regulationeukaryotic translation initiation factor 5A

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EIF5A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy
In eukaryotes, the polyamine pathway generates spermidine that activates the hypusination of the translation factor eukaryotic… 
2018
2018
Plasmacytoma variant translocation 1 (PVT1) regulates trophoblast viability, proliferation, and migration and is downregulated in spontaneous abortion
Human pregnancy is a complex biological process, and spontaneous abortion is the most common complication of pregnancy. LncRNAs… 
2017
2017
Hypusination of eIF5A as a Target for Antiviral Therapy.
V iruses are a recurring threat to human health worldwide. From highly prevalent diseases such as HIV, dengue, and influenza to… 
2011
2011
The role of eIF5A in protein synthesis
Comment on: Henderson A, et al. Proc Natl Acad Sci USA 2011; 108:6415-9. 
2010
2010
Pumpkin eIF5A isoforms interact with components of the translational machinery in the cucurbit sieve tube system.
In yeast, eIF5A, in combination with eEF2, functions at the translation step, during the protein elongation cycle. This result is… 
Review
2009
Review
2009
Cellular proteins and HIV-1 Rev function.
The human immunodeficiency virus (HIV-1) differentially controls viral protein expression at the level of splicing as well as… 
2005
2005
Modulation of Differentiation-related Gene 1 Expression by Cell Cycle Blocker Mimosine, Revealed by Proteomic Analysis*
l-Mimosine, a plant amino acid, can reversibly block mammalian cells at late G1 phase and has been found to affect translation of… 
Highly Cited
2003
Highly Cited
2003
Reversal of the Deoxyhypusine Synthesis Reaction
Deoxyhypusine synthase catalyzes the first step in hypusine (Nϵ-(4-amino-2-hydroxybutyl)lysine) synthesis in a single cellular… 
1996
1996
The subcellular distribution of eukaryotic translation initiation factor, eIF-5A, in cultured cells.
To gain insight into the role of the eukaryotic translation initiation factor, eIF-5A, we investigated the subcellular… 
Review
1994
Review
1994
Expression of initiation factor genes in mammalian cells.
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