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EIF4G1 gene

Known as: p220, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, Eukaryotic Translation Initiation Factor 4 Gamma, 1 Gene 
This gene is involved in the initiation of translation.
National Institutes of Health

Related topics

Related topics

7 relations
EIF4G1 protein, humanEukaryotic Initiation Factor-4GEukaryotic Translation Initiation Factor 4 Gamma 1Genetic Translation Process

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EIF4G1 wt Allele

Papers overview

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Highly Cited
2009
Highly Cited
2009
Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer
Inflammatory breast cancer (IBC) is the most lethal form of primary breast cancer. IBC lethality derives from generation of… 
Highly Cited
2008
Highly Cited
2008
eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy
Translation initiation factors have complex functions in cells that are not yet understood. We show that depletion of initiation… 
Highly Cited
2003
Highly Cited
2003
PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes.
It has previously been shown that influenza virus NS1 protein enhances the translation of viral but not cellular mRNAs. This… 
Highly Cited
2003
Highly Cited
2003
Distinct Regulation of Internal Ribosome Entry Site-mediated Translation following Cellular Stress Is Mediated by Apoptotic Fragments of eIF4G Translation Initiation Factor Family Members eIF4GI and…
Many cellular stresses lead to the inhibition of protein synthesis. Despite this, some cellular mRNAs are selectively translated… 
Highly Cited
2002
Highly Cited
2002
Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins.
Highly Cited
2002
Highly Cited
2002
Efficient Cleavage of Ribosome-Associated Poly(A)-Binding Protein by Enterovirus 3C Protease
ABSTRACT Poliovirus (PV) causes a rapid and drastic inhibition of host cell cap-dependent protein synthesis during infection… 
Review
2001
Review
2001
Control of translation by the target of rapamycin proteins.
Regulation of translation rates, the frequency with which a given mRNA is translated, plays an important role in the control of… 
Highly Cited
2000
Highly Cited
2000
A Novel Form of DAP5 Protein Accumulates in Apoptotic Cells as a Result of Caspase Cleavage and Internal Ribosome Entry Site-Mediated Translation
ABSTRACT Death-associated protein 5 (DAP5) (also named p97 and NAT1) is a member of the translation initiation factor 4G (eIF4G… 
Highly Cited
1999
Highly Cited
1999
Translation driven by an eIF4G core domain in vivo
Most eukaryotic mRNAs possess a 5′ cap structure (m7GpppN) and a 3′ poly(A) tail which promote translation initiation by binding… 
Highly Cited
1998
Highly Cited
1998
A Novel Functional Human Eukaryotic Translation Initiation Factor 4G
ABSTRACT Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a cap-binding protein complex consisting of three… 
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