FAQ

EIF3C gene

Known as: EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT C, EIF3C, EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT 8, FORMERLY 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
01220012017

Related topics

Related topics

3 relations
EIF3B wt AlleleEIF3I geneEukaryotic Translation Initiation Factor 3 Subunit B

Related mentions per year

Related mentions per year

1986-2018
19801990200020102020
EIF3C gene
Eukaryotic Translation Initiation Factor 3 Subunit B
EIF3B wt Allele
EIF3I gene

Papers overview

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2017
2017
Transcriptomic analyses of RNA‐binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma
RNA-binding proteins (RBPs) play fundamental roles in the RNA life cycle. The aberrant expression of RBPs is often observed in… (More)
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2017
2017
Decreasing Eukaryotic Initiation Factor 3C (EIF3C) Suppresses Proliferation and Stimulates Apoptosis in Breast Cancer Cell Lines Through Mammalian Target of Rapamycin (mTOR) Pathway
BACKGROUND Translation initiation is the rate limiting step of protein synthesis and is highly regulated. Eukaryotic initiation… (More)
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2015
2015
Structure of a Yeast 40S–eIF1–eIF1A–eIF3–eIF3j initiation complex
Eukaryotic translation initiation requires cooperative assembly of a large protein complex at the 40S ribosomal subunit. We have… (More)
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2013
2013
eIF3c: a potential therapeutic target for cancer.
Cancer cells are rapidly evolving due to their unstable genome, which contributes to the development of new cancer clones with… (More)
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2012
2012
The interaction between human initiation factor eIF3 subunit c and heat-shock protein 90: a necessary factor for translation mediated by the hepatitis C virus internal ribosome entry site.
Heat-shock protein 90 (Hsp90) is a molecular chaperone that plays a key role in the conformational maturation of various… (More)
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2006
2006
Schwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor subunit c (eIF3c).
The neurofibromatosis 2 (NF2) tumor suppressor protein, schwannomin or merlin, is commonly lost upon NF2 gene mutation in benign… (More)
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2005
2005
Induction and mode of action of the viral stress-inducible murine proteins, P56 and P54.
Mammalian cells respond to virus infection or other viral stresses, such as double-stranded (ds) RNA and interferons (IFN), by… (More)
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2004
2004
Efficient incorporation of eukaryotic initiation factor 1 into the multifactor complex is critical for formation of functional ribosomal preinitiation complexes in vivo.
Eukaryotic initiation factor 1 (eIF1) is a low molecular weight factor critical for stringent AUG selection in eukaryotic… (More)
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2004
2004
Physical association of eukaryotic initiation factor (eIF) 5 carboxyl-terminal domain with the lysine-rich eIF2beta segment strongly enhances its binding to eIF3.
The carboxyl-terminal domain (CTD) of eukaryotic initiation factor (eIF) 5 interacts with eIF1, eIF2beta, and eIF3c, thereby… (More)
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2001
2001
Arabidopsis eIF3e (INT-6) associates with both eIF3c and the COP9 signalosome subunit CSN7.
The Arabidopsis COP9 signalosome is a multisubunit repressor of photomorphogenesis that is conserved among eukaryotes. This… (More)
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