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EIF3B wt Allele

Known as: EIF3-P116, Eukaryotic Translation Initiation Factor 3, Subunit 9 (Eta, 116kD) Gene, MGC104664 
Human EIF3B wild-type allele is located in the vicinity of 7p22.3 and is approximately 25 kb in length. This allele, which encodes eukaryotic… Expand
National Institutes of Health

Related topics

Related topics

6 relations

Broader (1)

EIF3B gene
EIF3C geneEukaryotic Initiation Factor-3, Subunit 8Eukaryotic Translation Initiation Factor 3 Subunit BGenetic Translation Process
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Papers overview

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Highly Cited
2010
Highly Cited
2010
The indispensable N-terminal half of eIF3j/HCR1 co-operates with its structurally conserved binding partner eIF3b/PRT1-RRM and eIF1A in stringent AUG selection
Despite the recent progress in our understanding of the numerous functions of individual subunits of eukaryotic translation… Expand
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Highly Cited
2006
Highly Cited
2006
Interaction of the RNP1 Motif in PRT1 with HCR1 Promotes 40S Binding of Eukaryotic Initiation Factor 3 in Yeast
ABSTRACT We found that mutating the RNP1 motif in the predicted RRM domain in yeast eukaryotic initiation factor 3 (eIF3) subunit… Expand
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Review
2005
Review
2005
DIRS-1 and the other tyrosine recombinase retrotransposons
DIRS-1 is a retroelement from the slime mold Dictyostelium discoideum. Until recently only two related retrotransposons had been… Expand
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2002
2002
Characterization of plasmid pRT1 from Pyrococcus sp. strain JT1.
We discovered a 3,373-bp plasmid (pRT1) in the hyperthermophilic archaeon Pyrococcus sp. strain JT1. Two major open reading… Expand
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Highly Cited
2001
Highly Cited
2001
Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome binding
eIF3 binds to 40S ribosomal subunits and stimulates recruitment of Met‐tRNAiMet and mRNA to the pre‐initiation complex… Expand
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Highly Cited
1999
Highly Cited
1999
An internal open reading frame triggers nonsense‐mediated decay of the yeast SPT10 mRNA
Yeast cells containing a temperature‐sensitive mutation in the PRT1 gene were found to selectively stabilize mRNAs harboring… Expand
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Highly Cited
1998
Highly Cited
1998
Complex Formation by All Five Homologues of Mammalian Translation Initiation Factor 3 Subunits from Yeast Saccharomyces cerevisiae *
The PRT1, TIF34, GCD10, and SUI1 proteins ofSaccharomyces cerevisiae were found previously to copurify with eukaryotic… Expand
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Highly Cited
1998
Highly Cited
1998
PRT1 of Arabidopsis thaliana encodes a component of the plant N-end rule pathway.
Mutants in the PRT1 gene of Arabidopsis thaliana are impaired in the degradation of a normally short-lived intracellular protein… Expand
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Highly Cited
1994
Highly Cited
1994
Purified yeast translational initiation factor eIF-3 is an RNA-binding protein complex that contains the PRT1 protein.
Eukaryotic initiation factor-3 (eIF-3) plays a pivotal role in the initiation phase of protein synthesis where it promotes… Expand
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Highly Cited
1987
Highly Cited
1987
Molecular characterization of the yeast PRT1 gene in which mutations affect translation initiation and regulation of cell proliferation.
Several temperature-sensitive cell division cycle (cdc) mutations differentially affect the regulatory step for cell… Expand
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