Eukaryotic Translation Initiation Factor 3 Subunit B
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BackgroundMETTL3 is an RNA methyltransferase that mediates m6A modification and is implicated in mRNA biogenesis, decay, and… Expand Eukaryotic translation initiation factor 3 (eIF3) is a central player in recruitment of the pre-initiation complex (PIC) to mRNA… Expand Eukaryotic translation initiation requires cooperative assembly of a large protein complex at the 40S ribosomal subunit. We have… Expand Purpose: Discovery transcriptomic analyses suggest eukaryotic initiation factor 3b (eIF3b) is elevated in human bladder and… Expand Translation initiation factor eIF3 acts as the key orchestrator of the canonical initiation pathway in eukaryotes, yet its… Expand Despite the recent progress in our understanding of the numerous functions of individual subunits of eukaryotic translation… Expand Eukaryotic translation initiation factor (eIF)3 is the largest eIF (∼650 kDa), consisting of 10–13 different polypeptide subunits… Expand Mammalian eIF3 is a 700-kDa multiprotein complex essential for initiation of protein synthesis in eukaryotic cells. It consists… Expand Foot-and-mouth disease virus (FMDV) infection induces major changes in the host cell including the shutoff of cellular protein… Expand The binding of eIF2–GTP–tRNAiMet ternary complex (TC) to 40S subunits is impaired in yeast prt1‐1 (eIF3b) mutant extracts, but… Expand