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EHT 1864

Known as: EHT-1864, EHT1864 
National Institutes of Health

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2 relations

Broader (2)

PyronesQuinolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Faculty Opinions recommendation of Inhibition of female and male human detrusor smooth muscle contraction by the rac inhibitors EHT1864 and NSC23766.
  • R. Adam
  • Faculty Opinions – Post-Publication Peer Review…
  • 2020
  • Corpus ID: 218958107
2019
2019
New strategies for inhibition of non‐adrenergic prostate smooth muscle contraction by pharmacologic intervention
Inhibition of prostate smooth muscle contraction by α1‐adrenoceptor antagonists (α1‐blockers) is a first‐line medical treatment… 
2019
2019
Increased Rac1 activation in the enhanced carbachol-induced bronchial smooth muscle contraction of repeatedly antigen-challenged mice.
Recently, we demonstrated that Rac1 upregulation is involved in augmented bronchial smooth muscle (BSM) contractions of antigen… 
2019
2019
MP11-10 INHIBITION OF CHOLINERGIC, NEUROGENIC, AND NON-CHOLINERGIC/NON-NEUROGENIC DETRUSOR CONTRACTIONS BY THE RAC INHIBITOR EHT1864
INTRODUCTION AND OBJECTIVES: Lower urinary tract symptoms (LUTS) due to overactive bladder (OAB) are caused by involuntary… 
2018
2018
Inhibition of Rac family protein impairs colitis and colitis-associated cancer in mice.
The prevalence of inflammatory bowel disease (IBD) has increased worldwide and IBD has been demonstrated to promote the… 
2017
2017
Detection of Rac activity and inhibition of smooth muscle contraction by EHT1864 in the human trigone: Expanding the role of Rac GTPase in the lower urinay tract outflow region
2017
2017
DETECTION OF RAC ACTIVITY AND INHIBITION OF SMOOTH MUSCLE CONTRACTION BY THE RAC INHIBITOR EHT1864 IN THE HUMAN TRIGONE: IMPLICATIONS FOR RAC GTPASE IN BLADDER SMOOTH MUSCLE CONTRACTION: MP82‐14
2014
2014
The small GTPase Rac1 is required for smooth muscle contraction
The role of the small G‐protein Rac1 was investigated in smooth muscle, using a smooth muscle‐specific knockout mouse and… 
2013
2013
Regulation of Adherens Junctions in Trabecular Meshwork Cells by Rac GTPase and their influence on Intraocular Pressure.
Intercellular adherens junctions and cell-extracellular matrix interactions are presumed to influence aqueous humor (AH) drainage… 
2012
2012
Pan‐Selective Aptamers for the Family of Small GTPases
The members of the large family of small-GTP-binding proteins (GTPases) function as molecular switches and are involved in… 
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