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E7389

Known as: E 7389, E-7389 
A synthetic analogue of halichondrin B, a substance derived from a marine sponge (Lissodendoryx sp.) with antineoplastic activity. E7389 binds to the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Eribulin mesylate (E7389), a synthetic analogue of the marine natural product halichondrin B, is in phase III clinical trials for… Expand
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Highly Cited
2010
Highly Cited
2010
Eribulin mesylate (E7389) is a nontaxane microtubule dynamics inhibitor with a novel mechanism of action. In preclinical studies… Expand
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Highly Cited
2009
Highly Cited
2009
PURPOSE Eribulin mesylate (E7389), a non-taxane microtubule dynamics inhibitor, is a structurally simplified, synthetic analogue… Expand
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Highly Cited
2009
Highly Cited
2009
PURPOSE To evaluate the maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and pharmacokinetics of eribulin mesylate… Expand
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Highly Cited
2008
Highly Cited
2008
Eribulin (E7389), a synthetic analogue of halichondrin B in phase III clinical trials for breast cancer, binds to tubulin and… Expand
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2007
2007
C58 Eribulin (E7389, ER-086526, NSC-707389), a structurally-simplified synthetic analog of the biologically active macrocyclic… Expand
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2006
2006
The complex marine natural product halichondrin B was compared with NSC 707389 (E7389), a structurally simplified, synthetic… Expand
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Highly Cited
2005
Highly Cited
2005
E7389, which is in phase I and II clinical trials, is a synthetic macrocyclic ketone analogue of the marine sponge natural… Expand
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2005
2005
3036 Background: The California Cancer Consortium recently completed a Phase I pharmacokinetic (PK) and target validation (TV… Expand
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Highly Cited
2004
Highly Cited
2004
E7389, a macrocyclic ketone analog of the marine natural product halichondrin B, currently is undergoing clinical trials for… Expand
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