eribulin mesylate

Known as: eribulin (as mesylate), eribulin mesilate, eribulin monomethanesulfonate 
The mesylate salt of a synthetic analogue of halichondrin B, a substance derived from a marine sponge (Lissodendoryx sp.) with antineoplastic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2008-2018
010203020082018

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND A non-randomised, phase 2 study showed activity and tolerability of eribulin in advanced or metastatic soft-tissue… (More)
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Highly Cited
2015
Highly Cited
2015
PURPOSE This phase III randomized trial (ClinicalTrials.gov identifier: NCT00337103) compared eribulin with capecitabine in… (More)
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2014
2014
Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B and an inhibitor… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Treatments with survival benefit are greatly needed for women with heavily pretreated metastatic breast cancer… (More)
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2011
2011
Eribulin mesylate (Halaven; Eisai) — a synthetic analogue of the marine natural product halichondrin B that interferes with… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Eribulin inhibits microtubule dynamics via a mechanism distinct from that of other tubulin-targeting drugs, inducing… (More)
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2011
2011
Chemotherapy-induced neurotoxicity is a significant problem associated with successful treatment of many cancers. Tubulin is a… (More)
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Highly Cited
2010
Highly Cited
2010
Eribulin mesylate (E7389), a synthetic analogue of the marine natural product halichondrin B, is in phase III clinical trials for… (More)
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2010
2010
Eribulin mesylate (E7389) is a nontaxane microtubule dynamics inhibitor with a novel mechanism of action. In preclinical studies… (More)
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2009
2009
PURPOSE To evaluate the maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and pharmacokinetics of eribulin mesylate… (More)
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