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E6005

National Institutes of Health

Papers overview

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2018
2018
A dried blood spot assay with UPLC–MS/MS for the simultaneous determination of E6005, a phosphodiesterase 4 inhibitor, and its metabolite in human blood
2015
2015
A putative antipruritic mechanism of the phosphodiesterase‐4 inhibitor E6005 by attenuating capsaicin‐induced depolarization of C‐fibre nerves
E6005, a potent, selective phosphodiesterase (PDE) 4 inhibitor, has been developed as a novel topical agent of atopic dermatitis… 
2015
2015
Validation of a UPLC-MS/MS method for the simultaneous determination of E6005, a phosphodiesterase 4 inhibitor, and its metabolite in human plasma.
2015
2015
An inhaled phosphodiesterase 4 inhibitor E6005 suppresses pulmonary inflammation in mice.
2014
2014
Application of phosphodiesterase 4 inhibitor for atopic dermatitis.
キーワード:アトピー性皮膚炎,痒み,phosphodiesterase 4,E6005 エーザイ株式会社 筑波研究所(〒300 -2635 茨城県つくば市東光台 5 -1 -3) E-mail: n3 ishii@hhc.eisai.co.jp… 
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