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E2F4 protein, human

Known as: E2F-4, Transcription Factor E2F4, E2F transcription factor 4 protein, human 
Transcription factor E2F4 (413 aa, ~44 kDa) is encoded by the human E2F4 gene. This protein plays a role in the modulation of tumor suppressor… 
National Institutes of Health

Related topics

Related topics

12 relations
Cell CycleCell Cycle ControlCell NucleusDNA-Binding Proteins

Broader (1)

E2F4 Transcription Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Key signaling pathways, genes and transcription factors associated with hepatocellular carcinoma
The purpose of the present study was to investigate the underlying molecular mechanism of hepatocellular carcinoma (HCC) using… 
2013
2013
Functional impact of colorectal cancer-associated mutations in the transcription factor E2F4.
The transcription factor E2F4 plays a critical role in cell cycle progression of normal and cancerous intestinal epithelial cells… 
2005
2005
Proliferation-dependent expression of nuclear uracil-DNA glycosylase is mediated in part by E2F-4.
2002
2002
Active Nuclear Import and Export Pathways Regulate E2F-5 Subcellular Localization*
Epidermal keratinocyte differentiation is accompanied by differential regulation of E2F genes, including up-regulation of E2F-5… 
2002
2002
Expression of E2F-4 Gene in Colorectal Adenocarcinoma and Corresponding Covering Mucosa: An Immunohistochemistry, Image Analysis, and Immunoblot Study
E2F-4 is a transcription factor involved in the transition of the cell from the resting state (G0/G1) to the proliferative stage… 
2001
2001
Effect of Naturally Occurring E2F-4 Alterations on Transcriptional Activation and Proliferation in Transfected Cells
E2F is a family of transcription factors implicated in the regulation of gene expression required for progression through the G1… 
Review
2000
Review
2000
Cell Cycle and Transcriptional Control of Human Myeloid Leukemic Cells by Transforming Growth Factor Beta
TGFβ1 is a potent growth inhibitor of both primitive and more differentiated human myeloid leukemic cells. The extent of the… 
1998
1998
Site-directed mutant p21 proteins defective in both inhibition of E2F-regulated transcription and disruption of E2F-p130-cyclin-cdk2 complexes.
P21 is a regulatory protein that can contribute to cell cycle arrest by inhibiting the cyclin-dependent-kinases (cdks). However… 
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