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E2F4 protein, human

Known as: E2F-4, Transcription Factor E2F4, E2F transcription factor 4 protein, human 
Transcription factor E2F4 (413 aa, ~44 kDa) is encoded by the human E2F4 gene. This protein plays a role in the modulation of tumor suppressor… 
National Institutes of Health

Related topics

Related topics

12 relations
Cell CycleCell Cycle ControlCell NucleusDNA-Binding Proteins

Broader (1)

E2F4 Transcription Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Functional impact of colorectal cancer-associated mutations in the transcription factor E2F4.
The transcription factor E2F4 plays a critical role in cell cycle progression of normal and cancerous intestinal epithelial cells… 
2002
2002
Active Nuclear Import and Export Pathways Regulate E2F-5 Subcellular Localization*
Epidermal keratinocyte differentiation is accompanied by differential regulation of E2F genes, including up-regulation of E2F-5… 
2002
2002
Expression of E2F-4 Gene in Colorectal Adenocarcinoma and Corresponding Covering Mucosa: An Immunohistochemistry, Image Analysis, and Immunoblot Study
E2F-4 is a transcription factor involved in the transition of the cell from the resting state (G0/G1) to the proliferative stage… 
2001
2001
Effect of Naturally Occurring E2F-4 Alterations on Transcriptional Activation and Proliferation in Transfected Cells
E2F is a family of transcription factors implicated in the regulation of gene expression required for progression through the G1… 
2000
2000
Subcellular Compartmentalization of E2f Family Members Is Required for Maintenance of the Postmitotic State in Terminally Differentiated Muscle
Maintenance of cells in a quiescent state after terminal differentiation occurs through a number of mechanisms that regulate the… 
Review
2000
Review
2000
Cell Cycle and Transcriptional Control of Human Myeloid Leukemic Cells by Transforming Growth Factor Beta
TGFβ1 is a potent growth inhibitor of both primitive and more differentiated human myeloid leukemic cells. The extent of the… 
Highly Cited
1997
Highly Cited
1997
Specific regulation of E2F family members by cyclin-dependent kinases
The transcription factor E2F-1 interacts stably with cyclin A via a small domain near its amino terminus and is negatively… 
Highly Cited
1996
Highly Cited
1996
Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.
E2F transcription factors are key regulators of transcription during the cell cycle. E2F activity is regulated at the level of… 
Highly Cited
1996
Highly Cited
1996
Cell cycle-regulated repression of B-myb transcription: cooperation of an E2F site with a contiguous corepressor element.
B-myb belongs to a group of cell cycle genes whose transcription is repressed in G0/early G1 through a binding site for the… 
Highly Cited
1996
Highly Cited
1996
G1 cyclin/CDK-independent phosphorylation and accumulation of p130 during the transition from G1 to G0 lead to its association with E2F-4.
During the transition from G1 to G0, p130 undergoes a specific phosphorylation event-leading to p130-form 2- that is mediated by… 
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