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E2F1 protein, human

Known as: RBBP3 protein, human, E2F transcription factor 1 protein, human, Retinoblastoma-Binding Protein 3 
Transcription factor E2F1 (437 aa, ~47 kDa) is encoded by the human E2F1 gene. This protein is involved in the regulation of apoptosis, gene… 
National Institutes of Health

Related topics

Related topics

22 relations
ApoptosisCell CycleCell NucleusDNA-Binding Proteins

Broader (2)

E2F transcription factorsE2F1 Transcription Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The long noncoding RNA H19 promotes cell proliferation via E2F-1 in pancreatic ductal adenocarcinoma
ABSTRACT H19 is a long noncoding RNA differentially expressed in many tumors and participates in tumorigenesis. This study aimed… 
Highly Cited
2012
Highly Cited
2012
The p38 MAPK–MK2 Axis Regulates E2F1 and FOXM1 Expression after Epirubicin Treatment
E2F1 is responsible for the regulation of FOXM1 expression, which plays a key role in epirubicin resistance. Here, we examined… 
Review
2008
Review
2008
E2F1 in gliomas: a paradigm of oncogene addiction.
Highly Cited
2006
Highly Cited
2006
Brd2 is a TBP-associated protein and recruits TBP into E2F-1 transcriptional complex in response to serum stimulation
Brd2 is a novel protein kinase and plays a role in cell cycle-responsive transcription. Recent studies show that Brd2 contributes… 
Highly Cited
2003
Highly Cited
2003
Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice
The E2f1 transcription factor, which regulates genes required for S-phase entry, also induces apoptosis by transcriptional and… 
Highly Cited
2003
Highly Cited
2003
Octalkoxy-substituted phosphorus(V) triazatetrabenzcorroles via ring contraction of phthalocyanine precursors.
As part of efforts toward developing the synthesis of novel corrole analogues, the new triazatetrabenzcorrole (TBC) phosphorus(V… 
Highly Cited
2003
Highly Cited
2003
Ursodeoxycholic Acid Modulates E2F-1 and p53 Expression through a Caspase-independent Mechanism in Transforming Growth Factor β1-induced Apoptosis of Rat Hepatocytes*
Transforming growth factor β1 (TGF-β1)-induced hepatocyte apoptosis is associated with activation of E2F transcription factors… 
Highly Cited
2002
Highly Cited
2002
ARF Differentially Modulates Apoptosis Induced by E2F1 and Myc
ABSTRACT The ARF tumor suppressor participates in a p53-dependent apoptotic pathway that is stimulated in response to some… 
Review
1999
Review
1999
pRb and E2f-1 in mouse development and tumorigenesis.
1999
1999
Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation.
In mammalian cells, DNA damage induces robust changes in gene expression and these changes contribute to the proper execution of… 
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