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E2F1 protein, human

Known as: RBBP3 protein, human, E2F transcription factor 1 protein, human, Retinoblastoma-Binding Protein 3 
Transcription factor E2F1 (437 aa, ~47 kDa) is encoded by the human E2F1 gene. This protein is involved in the regulation of apoptosis, gene… 
National Institutes of Health

Related topics

Related topics

22 relations
ApoptosisCell CycleCell NucleusDNA-Binding Proteins

Broader (2)

E2F transcription factorsE2F1 Transcription Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
The long noncoding RNA H19 promotes cell proliferation via E2F-1 in pancreatic ductal adenocarcinoma
ABSTRACT H19 is a long noncoding RNA differentially expressed in many tumors and participates in tumorigenesis. This study aimed… 
2008
2008
Synthesis, structure, and electrocatalysis of diiron C-functionalized propanedithiolate (PDT) complexes related to the active site of [FeFe]-hydrogenases.
New C-functionalized propanedithiolate-type model complexes (1-8) have been synthesized by functional transformation reactions of… 
2003
2003
The E2F‐1 transcription factor is negatively regulated by its interaction with the MDMX protein
Several proteins with important roles in oncogenesis have been shown to regulate the function of the E2F‐1 transcription factor… 
2001
2001
Abnormal NF-kappaB signaling pathway with enhanced susceptibility to apoptosis in immortalized keratinocytes.
2001
2001
E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation
E2F-1 induces p53 accumulation and E2F-1 and p53 form a physical complex, which affects the ability of E2F-1 to activate… 
1999
1999
Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation.
In mammalian cells, DNA damage induces robust changes in gene expression and these changes contribute to the proper execution of… 
1999
1999
Overexpression of D-type cyclins, E2F-1, SV40 large T antigen and HPV16 E7 rescue cell cycle arrest of tsBN462 cells caused by the CCG1/TAFII250 mutation
tsBN462 cells, which have a point mutation in CCG1/TAFII250, a component of TFIID complex, arrest in G1 at the nonpermissive… 
1999
1999
Poly(ADP-ribose) polymerase upregulates E2F-1 promoter activity and DNA pol α expression during early S phase
E2F-1, a transcription factor implicated in the activation of genes required for S phase such as DNA pol α, is regulated by… 
1998
1998
E2F-1 and E2F-3 are functionally distinct in their ability to promote myeloid cell cycle progression and block granulocyte differentiation.
Interleukin 3 (IL-3)-dependent 32D.3 myeloid cells are an attractive model system for the analysis of hematopoietic cell growth… 
1995
1995
Epstein-Barr virus EBNA-LP and transcription regulation properties of pRB, p107 and p53 in transfection assays.
The EBNA-LP protein (also known as EBNA-5) of Epstein-Barr virus (EBV) has been reported previously to colocalize in the nuclei… 
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