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Extracellular pH (pH(e)) is lower in many tumors than in the corresponding normal tissue. The significance of acidic pH(e) in the… Expand We present experimental laboratory evidence and field observations of an autocatalyzed, programmed cell death (PCD) pathway in… Expand Dietary conjugated linoleic acid (CLA) reduces body fat in animals and some humans. Here we show that trans-10, cis-12 CLA, but… Expand BACKGROUND
Analysis of global changes in gene transcription and translation by systems-based genomics and proteomics approaches… Expand The anti-apoptotic molecule Bcl-2 is located in the mitochondrial and endoplasmic reticulum membranes as well as the nuclear… Expand Intercellular communication may be modulated by the rather rapid turnover and degradation of gap junction proteins, since many… Expand Human cathepsin K is a recently identified protein with high primary sequence homology to members of the papain cysteine protease… Expand Abstract— Cultured cells accumulate acridine orange (AO), which is a weak basic dye and a photosensi‐tizer, in lysosomes and… Expand The protein from chicken egg white that inhibits cysteine proteinases, and has been named 'cystatin', was purified by ovomucin… Expand 1. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) at a concentration of 0.5 mM had no effect on the serine… Expand