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E 3040
Known as:
E-3040
, E3040
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Benzothiazoles
Pyridines
Narrower (1)
E3040 sulfate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs
H. Shin
,
M. Takeda
,
+4 authors
H. Endou
Nephrology
2011
Corpus ID: 43761141
Aim: Hyperuricaemia is a significant factor in a variety of diseases, including gout and cardiovascular diseases. The kidney…
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2009
2009
Construction of Triple-Transfected Cells [Organic Anion-Transporting Polypeptide (OATP) 1B1/Multidrug Resistance-Associated Protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for Analysis of the Sinusoidal…
Masakazu Hirouchi
,
H. Kusuhara
,
R. Onuki
,
B. Ogilvie
,
A. Parkinson
,
Y. Sugiyama
Drug Metabolism And Disposition
2009
Corpus ID: 11792623
Multidrug resistance-associated protein (MRP) 3/ABCC3 and MRP4/ABCC4 are ATP-binding cassette (ABC) transporters expressed in the…
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Highly Cited
2005
Highly Cited
2005
Role of Breast Cancer Resistance Protein (Bcrp1/Abcg2) in the Extrusion of Glucuronide and Sulfate Conjugates from Enterocytes to Intestinal Lumen
Y. Adachi
,
Hiroshi Suzuki
,
A. Schinkel
,
Y. Sugiyama
Molecular Pharmacology
2005
Corpus ID: 9591434
The purpose of this study is to examine the significance of efflux transporters in the small intestine to extrude glucuronide (G…
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Highly Cited
2004
Highly Cited
2004
Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice.
Naomi Mizuno
,
Michiko Suzuki
,
+5 authors
Y. Sugiyama
Drug Metabolism And Disposition
2004
Corpus ID: 32460276
Murine breast cancer resistance protein 1 (Bcrp1) is expressed in the brush-border membrane of proximal tubule cells of the…
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2004
2004
Kinetic Analysis of Hepatobiliary Transport for Conjugated Metabolites in the Perfused Liver of Mutant Rats (EHBR) with Hereditary Conjugated Hyperbilirubinemia
O. Takenaka
,
T. Horie
,
Kazuo Kobayashi
,
Hiroshi Suzuki
,
Y. Sugiyama
Pharmaceutical Research
2004
Corpus ID: 22995718
AbstractPurpose. Previously, we found that the biliary excretion of the 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl…
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2001
2001
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
K. Oketani
,
N. Nagakura
,
K. Harada
,
T. Inoue
European Journal of Pharmacology
2001
Corpus ID: 46404775
Highly Cited
1999
Highly Cited
1999
Characterization of the Transport Properties of Cloned Rat Multidrug Resistance-associated Protein 3 (MRP3)*
T. Hirohashi
,
Hiroshi Suzuki
,
Yuichi Sugiyama
Journal of Biological Chemistry
1999
Corpus ID: 28986646
We have previously cloned rat MRP3 as an inducible transporter in the liver (Hirohashi, T., Suzuki, H., Ito, K., Ogawa, K., Kume…
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Highly Cited
1999
Highly Cited
1999
Contribution of organic anion transporting polypeptide to uptake of its possible substrates into rat hepatocytes.
H. Kouzuki
,
H. Suzuki
,
K. Ito
,
R. Ohashi
,
Y. Sugiyama
Journal of Pharmacology and Experimental…
1999
Corpus ID: 12160300
Organic anion transporting polypeptide (oatp1) has been cloned from rat liver as one of the transporters responsible for the…
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Highly Cited
1997
Highly Cited
1997
Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2…
K. Niinuma
,
O. Takenaka
,
+4 authors
Y. Sugiyama
Journal of Pharmacology and Experimental…
1997
Corpus ID: 32468151
UNLABELLED Eisai hyperbilirubinemic rat (EHBR) is a mutant strain with a hereditary defect in canalicular multispecific organic…
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Highly Cited
1995
Highly Cited
1995
Different biliary excretion systems for glucuronide and sulfate of a model compound; study using Eisai hyperbilirubinemic rats.
O. Takenaka
,
T. Horie
,
H. Suzuki
,
Y. Sugiyama
Journal of Pharmacology and Experimental…
1995
Corpus ID: 1450741
The disposition of conjugated metabolites (sulfate and glucuronide) was investigated in Eisai hyperbilirubinemic rats (EHBR) and…
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