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E 3040

Known as: E-3040, E3040 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2011
02419942011

Related topics

Related topics

2 relations

Broader (2)

BenzothiazolesPyridines

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
E 3040
Pyridines
Benzothiazoles

Papers overview

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2011
2011
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs.
AIM Hyperuricaemia is a significant factor in a variety of diseases, including gout and cardiovascular diseases. The kidney plays… (More)
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2009
2009
Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal…
Multidrug resistance-associated protein (MRP) 3/ABCC3 and MRP4/ABCC4 are ATP-binding cassette (ABC) transporters expressed in the… (More)
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2005
2005
Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen.
The purpose of this study is to examine the significance of efflux transporters in the small intestine to extrude glucuronide (G… (More)
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2004
2004
Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice.
Murine breast cancer resistance protein 1 (Bcrp1) is expressed in the brush-border membrane of proximal tubule cells of the… (More)
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Highly Cited
2003
Highly Cited
2003
ABCG2 transports sulfated conjugates of steroids and xenobiotics.
The mechanism for the cellular extrusion of sulfated conjugates is still unknown. In the present study, we investigated whether… (More)
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2001
2001
Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide.
Intravenous administration of lipopolysaccharide to rats that had been immunized with lipopolysaccharide induced hemorrhagic… (More)
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Highly Cited
1999
Highly Cited
1999
Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).
We have previously cloned rat MRP3 as an inducible transporter in the liver (Hirohashi, T., Suzuki, H., Ito, K., Ogawa, K., Kume… (More)
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1997
1997
Carrier-mediated active transport of the glucuronide and sulfate of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) into rat liver: quantitative comparison of…
The hepatic uptake of glucuronic acid and sulfate conjugates of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl… (More)
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1995
1995
Different biliary excretion systems for glucuronide and sulfate of a model compound; study using Eisai hyperbilirubinemic rats.
The disposition of conjugated metabolites (sulfate and glucuronide) was investigated in Eisai hyperbilirubinemic rats (EHBR) and… (More)
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1995
1995
Kinetic Analysis of Hepatobiliary Transport for Conjugated Metabolites in the Perfused Liver of Mutant Rats (EHBR) with Hereditary Conjugated Hyperbilirubinemia
Purpose. Previously, we found that the biliary excretion of the 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl… (More)
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