Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

E 3040

Known as: E-3040, E3040 
 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

BenzothiazolesPyridines

Narrower (1)

E3040 sulfate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Interactions of urate transporter URAT1 in human kidney with uricosuric drugs
Aim:  Hyperuricaemia is a significant factor in a variety of diseases, including gout and cardiovascular diseases. The kidney… Expand
2009
2009
Construction of Triple-Transfected Cells [Organic Anion-Transporting Polypeptide (OATP) 1B1/Multidrug Resistance-Associated Protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for Analysis of the Sinusoidal…
Multidrug resistance-associated protein (MRP) 3/ABCC3 and MRP4/ABCC4 are ATP-binding cassette (ABC) transporters expressed in the… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Highly Cited
2005
Highly Cited
2005
Role of Breast Cancer Resistance Protein (Bcrp1/Abcg2) in the Extrusion of Glucuronide and Sulfate Conjugates from Enterocytes to Intestinal Lumen
The purpose of this study is to examine the significance of efflux transporters in the small intestine to extrude glucuronide (G… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Highly Cited
2004
Highly Cited
2004
Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice.
Murine breast cancer resistance protein 1 (Bcrp1) is expressed in the brush-border membrane of proximal tubule cells of the… Expand
2004
2004
Kinetic Analysis of Hepatobiliary Transport for Conjugated Metabolites in the Perfused Liver of Mutant Rats (EHBR) with Hereditary Conjugated Hyperbilirubinemia
AbstractPurpose. Previously, we found that the biliary excretion of the 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl… Expand
2001
2001
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
In vitro pharmacological profiles of E3040, 6-hydroxy-5, 7-dimethyl-2-(methylamino)-4-(3-pyridylmethyl) benzothiazole were… Expand
Highly Cited
1999
Highly Cited
1999
Characterization of the Transport Properties of Cloned Rat Multidrug Resistance-associated Protein 3 (MRP3)*
We have previously cloned rat MRP3 as an inducible transporter in the liver (Hirohashi, T., Suzuki, H., Ito, K., Ogawa, K., Kume… Expand
  • figure 1
  • figure 2
  • table I
  • figure 4
  • figure 3
Highly Cited
1999
Highly Cited
1999
Contribution of organic anion transporting polypeptide to uptake of its possible substrates into rat hepatocytes.
Organic anion transporting polypeptide (oatp1) has been cloned from rat liver as one of the transporters responsible for the… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • figure 4
Highly Cited
1997
Highly Cited
1997
Kinetic analysis of the primary active transport of conjugated metabolites across the bile canalicular membrane: comparative study of S-(2,4-dinitrophenyl)-glutathione and 6-hydroxy-5,7-dimethyl-2…
UNLABELLED Eisai hyperbilirubinemic rat (EHBR) is a mutant strain with a hereditary defect in canalicular multispecific organic… Expand
  • figure 1
  • figure 3
  • figure 5
  • table 1
  • figure 7
Highly Cited
1995
Highly Cited
1995
Different biliary excretion systems for glucuronide and sulfate of a model compound; study using Eisai hyperbilirubinemic rats.
The disposition of conjugated metabolites (sulfate and glucuronide) was investigated in Eisai hyperbilirubinemic rats (EHBR) and… Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE