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Duplicons

Known as: Duplicon 
 
National Institutes of Health

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Segmental Duplications, Genomic

Papers overview

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2012
2012
Experimental definition of a clustered regularly interspaced short palindromic duplicon in Escherichia coli.
We analyzed sequences of newly inserted repeats in an Escherichia coli CRISPR (clustered regularly interspaced short palindromic… Expand
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2007
2007
Human subtelomeric duplicon structure and organization
BackgroundHuman subtelomeric segmental duplications ('subtelomeric repeats') comprise about 25% of the most distal 500 kb and 80… Expand
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2007
2007
Evolutionary history of chromosome 11 featuring four distinct centromere repositioning events in Catarrhini.
Panels of BAC clones used in FISH experiments allow a detailed definition of chromosomal marker arrangement and orientation… Expand
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2006
2006
Copy number variation in regions flanked (or unflanked) by duplicons among patients with developmental delay and/or congenital malformations; detection of reciprocal and partial Williams-Beuren…
Duplicons, that is, DNA sequences with minimum length 10 kb and a high sequence similarity, are known to cause unequal homologous… Expand
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2005
2005
Evidence for widespread reticulate evolution within human duplicons.
Approximately 5% of the human genome consists of segmental duplications that can cause genomic mutations and may play a role in… Expand
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Highly Cited
2002
Highly Cited
2002
Human chromosome 15q11-q14 regions of rearrangements contain clusters of LCR15 duplicons
Six breakpoint regions for rearrangements of human chromosome 15q11-q14 have been described. These rearrangements involve… Expand
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2002
2002
A 76-kb duplicon maps close to the BCR gene on chromosome 22 and the ABL gene on chromosome 9: possible involvement in the genesis of the Philadelphia chromosome translocation.
A patient with a typical form of chronic myeloid leukemia was found to carry a large deletion on the derivative chromosome 9q… Expand
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2001
2001
Additional complexity on human chromosome 15q: identification of a set of newly recognized duplicons (LCR15) on 15q11-q13, 15q24, and 15q26.
Several cytogenetic alterations affect the distal part of the long arm of human chromosome 15, including recurrent rearrangements… Expand
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2001
2001
Additional Complexity on Human Chromosome 15 q : Identification of a Set of Newly Recognized Duplicons ( LCR 15 ) on 15 q 11 – q 13 , 15 q 24 , and 15 q 26
Miguel Angel Pujana, Marga Nadal, Mònica Gratacòs, Belén Peral, Katalin Csiszar, Rogelio González-Sarmiento, Lauro Sumoy, and… Expand
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Review
2000
Review
2000
Structure of chromosomal duplicons and their role in mediating human genomic disorders.
Chromosome-specific low-copy repeats, or duplicons, occur in multiple regions of the human genome. Homologous recombination… Expand
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