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Drug Resistance, Neoplasm

Known as: Drug Resistance, Antineoplastic, Neoplasm Drug Resistance, Antineoplastic Drug Resistance 
Resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.
National Institutes of Health

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MdaB protein, E coli
aspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells.
2001
2001
Selection and characterization of a high-activity ribozyme directed against the antineoplastic drug resistance–associated ABC transporter BCRP/MXR/ABCG2
Breast cancer resistance protein (BCRP) is a recently identified new member of the superfamily of ATP-binding cassette… 
Highly Cited
2000
Highly Cited
2000
Doxorubicin-resistant variants of human prostate cancer cell lines DU 145, PC-3, PPC-1, and TSU-PR1: characterization of biochemical determinants of antineoplastic drug sensitivity.
Intrinsic and acquired antineoplastic drug resistance remain a major problem for advanced prostate cancer treatment. In order to… 
Review
1998
Review
1998
Pi-class glutathione S-transferase: regulation and function.
Highly Cited
1994
Highly Cited
1994
Involvement of Jun and Fos proteins in regulating transcriptional activation of the human pi class glutathione S-transferase gene in multidrug-resistant MCF7 breast cancer cells.
Elevated levels of the human pi class glutathione S-transferase (GSTP1-1) have been implicated in the development of… 
Review
1993
Review
1993
Clinical reversal of drug resistance in ovarian cancer.
Human ovarian cancer cell lines and relevant in vivo model systems have been used to identify mechanisms of resistance associated… 
Highly Cited
1991
Highly Cited
1991
A phase I clinical trial of novobiocin, a modulator of alkylating agent cytotoxicity.
Antineoplastic drug resistance is a major obstacle to improved treatment of most adult cancers in humans. Novobiocin, an… 
Review
1991
Review
1991
Antineoplastic drug resistance in brain tumors.
1990
1990
Glutathione S-transferases and drug resistance
1989
1989
Glutathione S-transferases and antineoplastic drug resistance
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