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Drug Interactions

Known as: Interaction, Drug, INTERACTION DRUG (NOS), DRUG INTERACTION (NOS) 
A change in the way a drug acts in the body when taken with certain other drugs, herbals, or foods, or when taken with certain medical conditions… 
National Institutes of Health

Related topics

Related topics

20 relations

Narrower (5)

Adverse drug interactionDrug PotentiationDrug SynergismFood-Drug Interactions
Adverse reaction to drugDrug KineticsMetabolic Detoxication, Phase IMetabolism

Broader (3)

Pharmacodynamicspharmacology and toxicologyphysical chemical interaction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines
Objective To identify the number of drug-disease and drug-drug interactions for exemplar index conditions within National… 
Highly Cited
2012
Highly Cited
2012
Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions
The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are… 
Review
2010
Review
2010
Sandwich-cultured hepatocytes: an in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity
Sandwich-cultured hepatocytes (SCH) are a powerful in vitro tool that can be utilized to study hepatobiliary drug transport… 
Review
2009
Review
2009
Predicting Drug–Drug Interactions: An FDA Perspective
Pharmacokinetic drug interactions can lead to serious adverse events, and the evaluation of a new molecular entity’s drug–drug… 
Highly Cited
2007
Highly Cited
2007
Proposal for a New Tool to Evaluate Drug Interaction Cases
The assessment of causation for a potential drug interaction requires thoughtful consideration of the properties of both the… 
Review
2007
Review
2007
Metabolic drug interactions with newer antipsychotics: a comparative review.
Newer antipsychotics introduced in clinical practice in recent years include clozapine, risperidone, olanzapine, quetiapine… 
Review
2005
Review
2005
Predicting in vivo drug interactions from in vitro drug discovery data
In vitro screening for drugs that inhibit cytochrome P450 enzymes is well established as a means for predicting potential… 
Review
2002
Review
2002
Mechanisms of Clinically Relevant Drug Interactions Associated with Tacrolimus
The clinical management of tacrolimus, a macrolide used as immunosuppressant after transplantation, is complicated by its narrow… 
Highly Cited
2000
Highly Cited
2000
Response Surface Model for Anesthetic Drug Interactions
Background Anesthetic drug interactions traditionally have been characterized using isobolographic analysis or multiple logistic… 
Review
1997
Review
1997
Drug Interactions with Grapefruit Juice
SummarySome drugs demonstrate a significantly greater (up to 3-fold) mean oral bioavailability on coadministration with… 
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