Metabolic Detoxication, Phase I

Known as: Metabolic Detoxification, Phase I, Detoxication, Oxidative Metabolic, Metabolic Detoxication, Oxidative 
Functionalization of exogenous substances to prepare them for conjugation in PHASE II DETOXIFICATION. Phase I enzymes include CYTOCHROME P450 enzymes… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
02419852017

Papers overview

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2007
2007
Changes in the gene transcription of stress response genes in resident fish can be powerful biomarkers for the identification of… (More)
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2007
2007
Spanish black radish (Raphanus sativus L. var. niger) is a member of the Cruciferae family that also contains broccoli and… (More)
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2007
2007
Dietary specialization is thought to be rare in mammalian herbivores because of limitations of their detoxification system in… (More)
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2006
2006
Farnesoid X receptor knockout (Fxr(-/-)) mice cannot upregulate the bile salt export pump in bile acid loading or cholestatic… (More)
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2006
2006
Liver genes related to phase I and phase II detoxification, as well as inhibition of reactive oxygen species (ROS) production… (More)
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2005
2005
Complex mixtures of carcinogenic metalloids, such as arsenic, and polycyclic aromatic hydrocarbons or halogenated aromatic… (More)
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2004
2004
Retinoid X receptor alpha (RXRalpha) plays a pivotal role in regulating liver metabolism. RXRalpha-mediated gene expression… (More)
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2004
2004
CYP6B4, a cytochrome P450 gene from the tiger swallowtail Papilio glaucus, is transcriptionally induced in the midgut by dietary… (More)
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2002
2002
The genetic polymorphism of glutathione-S-transferase M1 (GSTM1) and glutathione-S-transferase T1 (GSTT1) genes and the… (More)
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1998
1998
Cytochrome P450 2E1 (CYP2E1) is a phase I detoxification enzyme, which is induced by chronic alcohol consumption. It is involved… (More)
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