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Doxylamine

Known as: Doxilamina, Dossilamina, Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether 
A first generation ethanolamine with antiinflammatory, sedative and antihistamine properties. Doxylamine competitively inhibits the histamine 1 (H1… 
National Institutes of Health

Related topics

Related topics

28 relations
Acetaminophen 325 MG / doxylamine succinate 6.25 MG / Phenylephrine Hydrochloride 5 MG Oral CapsuleDextromethorphan Hydrobromide 1 MG/ML / doxylamine succinate 0.417 MG/ML Oral SolutionDoxylamine:PrThr:Pt:Urine:OrdDrug Allergy

Broader (2)

AntiemeticsHistamine H1 Antagonists

Narrower (7)

NyquilSyndolUnisomdicyclomine, doxylamine, pyridoxine drug combination

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2000
Review
2000
Critical appraisal of drug therapy for nausea and vomiting of pregnancy: II. Efficacy and safety of diclectin (doxylamine-B6).
Nausea and vomiting of pregnancy is the most common condition in pregnancy and affects up to 80% of all pregnant women. There are… 
Highly Cited
1994
Highly Cited
1994
Enhanced cancer growth in mice administered daily human-equivalent doses of some H1-antihistamines: predictive in vitro correlates.
BACKGROUND Present studies of drug-induced tumor growth promotion have evolved from earlier investigations into the mechanism of… 
1993
1993
Non-traumatic rhabdomyolysis complicating antihistamine overdose.
Antihistamines are common over the counter medications which are frequently involved in overdoses. The usual clinical course is… 
1989
1989
Congenital anomalies associated with maternal exposure to oxydemeton-methyl.
1986
1986
Doxylamine metabolism in rat and monkey.
Metabolites of doxylamine obtained with rat-liver homogenate in vitro and from urine of Wistar rats and squirrel monkeys in vivo… 
Review
1985
Review
1985
Maternal Drugs and Congenital Heart Disease
Congenital heart disease comprises one-third of all major birth defects. Prevalence estimates depend on the definition of the… 
Highly Cited
1984
Highly Cited
1984
A study of the potential genotoxicity of methapyrilene and related antihistamines using the hepatocyte/DNA repair assay.
1984
1984
The innocent bystander: Doxylamine/dicyclomine/pyridoxine and congenital limb defects
The antinausea drug combination, doxylamine/dicyclomine/pyridoxine (Debendox or Bendectin [US]), has been withdrawn from the… 
1983
1983
False-positive EMIT indication of opiates and methadone in a doxylamine intoxication.
The EMIT-dau for methadone and the EMIT-ST for opiates (both EMITs from Syva-Merck) gave false-positive results when applied to… 
1981
1981
CONGENITAL ANOMALIES IN RELATION TO THE USE OF DOXYLAMINE/DICYCLOMINE AND OTHER ANTENATAL FACTORS AN ONGOING PROSPECTIVE STUDY
Recent publicity regarding possible teratogenic effects of the doxylamine/dicyclomine/pyridoxine combination (Debendox) has led… 
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