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Doxercalciferol
Known as:
1-alpha-hydroxyvitamin D2
, 1?-Hydroxyergocalciferol
, 1 alpha-hydroxyergocalciferol
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A synthetic analog of vitamin D with potential antineoplastic activity. In the liver, doxercalciferol is converted to its biologically active vitamin…
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National Institutes of Health
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Related topics
Related topics
9 relations
Broader (3)
Bone Density Conservation Agents
Ergocalciferols
Vitamins
Decreased Renal Ca++ Excretion [PE]
Drug toxicity
Hypercalcemia
Hyperparathyroidism
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Narrower (1)
Hectorol
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Comparative effects of doxercalciferol (1α-hydroxyvitamin D₂) versus calcitriol (1α,25-dihydroxyvitamin D₃) on the expression of transporters and enzymes in the rat in vivo.
E. Chow
,
Myrte Sondervan
,
Cheng Jin
,
Geny Martha Maria Groothuis
,
K. S. Pang
Journal of Pharmacy and Science
2011
Corpus ID: 206149577
Effects of 1.28 nmol/kg doxercalciferol [1α(OH)D₂], a synthetic vitamin D₂ analog that undergoes metabolic activation to 1α,25…
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Highly Cited
2010
Highly Cited
2010
Vitamin D insufficiency is prevalent among pregnant African American adolescents.
L. Davis
,
Shih-chen Chang
,
Jeri Mancini
,
Maureen Schulman Nathanson
,
F. Witter
,
K. O’Brien
Journal of Pediatric and Adolescent Gynecology
2010
Corpus ID: 32887427
2008
2008
Phase II study of doxercalciferol for the treatment of myelodysplastic syndrome
A. Petrich
,
B. Kahl
,
H. Bailey
,
KyungMann Kim
,
N. Turman
,
M. Juckett
Leukemia and Lymphoma
2008
Corpus ID: 22681959
We conducted a phase II trial of doxercalciferol, a vitamin D2 analogue, in 15 patients with MDS. Each received doxercalciferol…
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2005
2005
Molecular mechanism of the vitamin D antagonistic actions of (23S)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone depends on the primary structure of the carboxyl-terminal region of the vitamin d…
E. Ochiai
,
D. Miura
,
+6 authors
S. Ishizuka
Molecular Endocrinology
2005
Corpus ID: 36434271
We reported that (23S)-25-dehydro-1alpha-hydroxyvitamin D(3)-26,23-lactone (TEI-9647) antagonizes vitamin D receptor (VDR…
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2004
2004
Effectiveness of 1alpha-hydroxyvitamin D2 in inhibiting tumor growth in a murine transgenic pigmented ocular tumor model.
D. Albert
,
Amit Kumar
,
+5 authors
Sarit M. Patel
A M A Archives of Ophthalmology
2004
Corpus ID: 36112843
OBJECTIVE To study the effectiveness of the vitamin D analogue 1alpha-hydroxyvitamin D(2) (1alpha-OH-D(2)) in inhibiting ocular…
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2003
2003
Dramatic enhancement of antagonistic activity on vitamin D receptor: a double functionalization of 1alpha-hydroxyvitamin D3 26,23-lactones.
Nozomi Saito
,
H. Saito
,
+7 authors
A. Kittaka
Organic Letters
2003
Corpus ID: 25426655
The synthesis of novel vitamin D receptor antagonists, 24-methyl-1alpha-hydroxyvitamin D(3) 26,23-lactones, is reported. We found…
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2002
2002
Toxicity and dose-response studies of 1alpha-hydroxyvitamin D2 in a retinoblastoma xenograft model.
R. Grostern
,
P. Bryar
,
+6 authors
D. Albert
A M A Archives of Ophthalmology
2002
Corpus ID: 25358937
BACKGROUND Although calcitriol (1,25-dihydroxycholecalciferol) and vitamin D(2) inhibit retinoblastoma growth in the athymic…
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1995
1995
Metabolism of 1 alpha-hydroxyvitamin D2 to activated dihydroxyvitamin D 2 metabolites decreases endogenous 1 alpha, 25-dihydroxyvitamin D 3 in rats and monkeys.
J. Knutson
,
B. Hollis
,
L. Levan
,
C. Valliere
,
K. Gould
,
C. Bishop
Endocrinology
1995
Corpus ID: 31521354
The vitamin D analog 1 alpha-hydroxyvitamin D2 (1 alpha-OHD2) is under development for the treatment of secondary…
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1982
1982
Observations on the dietary practices of Asians in the United Kingdom.
W. P. Stephens
,
P. Klimiuk
,
S. Warrington
,
J. L. Taylor
Human nutrition. Applied nutrition
1982
Corpus ID: 7338697
The efficacy of a health education campaign to improve the vitamin D status of Asians has been assessed. The average daily…
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1978
1978
Direct C-1 hydroxylation of vitamin D compounds: convenient preparation of 1alpha-hydroxyvitamin D3, 1alpha, 25-dihydroxyvitamin D3, and 1alpha-hydroxyvitamin D2.
H. Paaren
,
D. E. Hamer
,
H. Schnoes
,
H. DeLuca
Proceedings of the National Academy of Sciences…
1978
Corpus ID: 38820536
An efficient procedure for the direct C-1 hydroxylation of vitamin D compounds has been developed. The method involves conversion…
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