Dolasetron

Known as: octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl 1H-indole-3-carboxylate, indole-3-carboxylic acid, ester with (8R)-hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one, Dolasétron 
An indole derivative and a potent serotonin 5-HT3 receptor antagonist with anti-emetic property. Dolasetron blocks the activity of serotonin released… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
Highly Cited
2009
Highly Cited
2009
BACKGROUND Palonosetron is a second-generation 5-hydroxytryptamine 3 (5-HT(3))-receptor antagonist that has shown better efficacy… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Part I of this article discussed the potential functional importance of genetic mutations and alleles of the human cytochrome… (More)
Is this relevant?
2007
2007
A 52-year-old woman with hypertension and Graves' disease was scheduled for surgical removal of a meningioma. Intraoperative… (More)
Is this relevant?
2004
2004
The opioid receptor antagonist naltrexone and the antiemetic 5-HT(3) receptor antagonist dolasetron are ketonic drugs that are… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Palonosetron, a highly selective and potent 5-HT(3) receptor antagonist with a strong binding affinity and a long… (More)
Is this relevant?
2002
2002
UNLABELLED We designed this study to assess the efficacy of dolasetron compared with clonidine and placebo in prophylaxis of… (More)
Is this relevant?
2002
2002
UNLABELLED In this prospective, randomized, double-blinded, placebo-controlled study, we compared the incidence of emesis and 48… (More)
Is this relevant?
Review
2000
Review
2000
Pain, nausea and vomiting are frequently listed by patients as their most important perioperative concerns. With the change in… (More)
  • figure 1
  • table II
  • table I
  • table III
  • table III
Is this relevant?
Highly Cited
1991
Highly Cited
1991
We have previously reported that serotonin (5-hydroxytryptamine [5HT]) alters cultured bovine pulmonary artery smooth muscle cell… (More)
Is this relevant?