Skip to search formSkip to main contentSkip to account menu

Dolasetron

Known as: octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl 1H-indole-3-carboxylate, indole-3-carboxylic acid, ester with (8R)-hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one, Dolasétron 
An indole derivative and a potent serotonin 5-HT3 receptor antagonist with anti-emetic property. Dolasetron blocks the activity of serotonin released… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (4)

AntiemeticsIndolesQuinolizinesSerotonin Antagonists
Dolasetron 50 MG Oral Tablet [Anzemet]Drug AllergyNauseaSerotonin 3 Receptor Antagonists [MoA]

Narrower (2)

MDL 73,147EFdolasetron mesylate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Chemotherapy-induced nausea and vomiting-associated hospital and ER visits in real-world practice: Palonosetron versus other 5-HT3-RA anti-emetic regimens.
9127 Background: Palonosetron (2nd generation 5-HT3-RA) and dolasetron, granisetron, and ondansetron (1st generation 5-HT3-RAs… 
Review
2009
Review
2009
Acustimulation of P 6 : an antiemetic alternative with no risk of drug-induced side-effects
Postoperative nausea and vomiting (PONV) is one of the most common complications after general anaesthesia, mainly triggered by… 
2009
2009
Electrospun Fiber-Based Drug Delivery System
Nausea and vomiting are common side effects of chemotherapy and surgery. Ondansetron (OND) is an anti-emetic drug that helps… 
2008
2008
Effects of ondansetron alone and in combination with domperidone in the prevention of chemotherapy-induced nausea and vomiting in breast cancer patients
The efficacy and safety of ondansetron, administered alone and in combination with domperidone to prevent chemotherapy-induced… 
2008
2008
Dolasetron and QT interval.
We read with interest the case report by Rochford et al .1 However, we are concerned that the title associates dolasetron… 
2008
2008
Quinuclidine-4-ylmethyl 1H- indole-3-carboxylate derivatives as α7 nicotinic acetylcholine receptor ligands for the treatment of Alzheimer's disease
The present invention relates to nicotinic acetylcholine receptors (nAChRs), for example, specific nicotinic receptor subtypes… 
2006
2006
Relative efficacy of ondansetron, granisetron, dolasetron and palonosetron in controlling acute nausea and vomiting associated with platinum-based chemotherapy.
1997
1997
Prevention of acute emesis in cancer patients following high-dose cisplatin with the combination of oral dolasetron and dexamethasone.
PURPOSE Dolasetron is a 5-HT3 antagonist antiemetic with active oral and intravenous formulations. The effects of this class are… 
1991
1991
Utilisation de quelques esters de l'hexahydro-8-hydroxy-2,6-méthano-2H-quinolizin-3(4H)-one et des composés apparentés pour le préparation des médicaments pour le traitement des maladies cognitives
1987
1987
Esters of hexahydro-8-hydroxy-2,6-methylene-2H-quinolizin-3(4H)-one and related compounds
The present invention is methylene (4H) on a set of hexahydro-8-hydroxy -2,6- -2H- quinolizin -3-- esters and related compounds…