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dolasetron mesylate

Known as: 1H-indole-3-carboxylic acid, (6R,9AS)-octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, rel-, methanesulfonate, hydrate (1:1:1), dolasetron mesylate monohydrate, dolasetron mesilate monohydrate 
An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, dolasetron mesylate competitively blocks the action of… Expand
National Institutes of Health

Papers overview

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2006
2006
BACKGROUND Postoperative nausea and vomiting (PONV) is one of the most frequent complications after general anaesthesia. Single… Expand
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Highly Cited
2002
Highly Cited
2002
Discute-se a avaliacao de politicas de atencao primaria, a partir da analise do caso de implantacao do Programa Saude da Familia… Expand
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1997
1997
BACKGROUND Intravenous dolasetron mesilate has shown efficacy in the prevention of postoperative nausea and vomiting (PONV) when… Expand
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1997
1997
The newer 5-hydroxytryptamine type 3 (5-HT3) antagonists are sometimes considered for routine prophylaxis of postoperative nausea… Expand
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Highly Cited
1997
Highly Cited
1997
PURPOSE To compare the efficacy of dolasetron and ondansetron in controlling nausea and vomiting in the first 24 hours; to… Expand
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Highly Cited
1996
Highly Cited
1996
PURPOSE To assess the comparative antiemetic efficacy of single-dose intravenous (IV) dolasetron mesylate and ondansetron in… Expand
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Highly Cited
1996
Highly Cited
1996
A single-blind, randomized, five-way cross-over, safety and tolerability trial was conducted to determine whether intravenous (i… Expand
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1996
1996
Dolasetron mesilate [(2 alpha, 6 alpha, 8 alpha, 9a beta)-octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-c arboxylate… Expand
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1996
1996
This multicentre, double-blind, double-dummy, randomised trial was designed to compare the efficacy and safety of single… Expand
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1994
1994
PURPOSE This dose-ranging trial of intravenous dolasetron mesylate (MDL73,147EF) was performed to determine its adverse and… Expand
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