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dolasetron mesylate

Known as: 1H-indole-3-carboxylic acid, (6R,9AS)-octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, rel-, methanesulfonate, hydrate (1:1:1), dolasetron mesylate monohydrate, dolasetron mesilate monohydrate 
An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, dolasetron mesylate competitively blocks the action of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The aim of this study was to identify the prognostic variables in mucosal melanoma of the head and neck. 
Highly Cited
2002
Highly Cited
2002
This article discusses the evaluation of primary health care policies based on a case study of the Family Health Program in… Expand
Highly Cited
2000
Highly Cited
2000
Administration of the 5-hydroxytryptamine 3 receptor class of antiemetic agents has been associated with prolongation in the QRS… Expand
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Highly Cited
1997
Highly Cited
1997
Background: Intravenous dolasetron mesilate has shown efficacy in the prevention of postoperative nausea and vomiting (PONV) when… Expand
1997
1997
PurposeTo compare the efficacy, safety, and tolerability of dolasetron mesilate with placebo for the treatment of postoperative… Expand
Highly Cited
1996
Highly Cited
1996
PURPOSE To assess the comparative antiemetic efficacy of single-dose intravenous (IV) dolasetron mesylate and ondansetron in… Expand
Highly Cited
1996
Highly Cited
1996
This multicentre, double-blind, double-dummy, randomised trial was designed to compare the efficacy and safety of single… Expand
Highly Cited
1996
Highly Cited
1996
A single-blind, randomized, five-way cross-over, safety and tolerability trial was conducted to determine whether intravenous (i… Expand
Highly Cited
1996
Highly Cited
1996
Dolasetron mesilate [(2 alpha, 6 alpha, 8 alpha, 9a beta)-octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-c arboxylate… Expand
Highly Cited
1994
Highly Cited
1994
PURPOSE This dose-ranging trial of intravenous dolasetron mesylate (MDL73,147EF) was performed to determine its adverse and… Expand