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dolasetron mesylate
Known as:
1H-indole-3-carboxylic acid, (6R,9AS)-octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, rel-, methanesulfonate, hydrate (1:1:1)
, dolasetron mesylate monohydrate
, dolasetron mesilate monohydrate
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An indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, dolasetron mesylate competitively blocks the action of…
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National Institutes of Health
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Related topics
Related topics
9 relations
Broader (3)
Dolasetron
Indoles
Quinolizines
Dolasetron 50 MG Oral Tablet [Anzemet]
Drug Allergy
Nausea
Serotonin 3 Receptor Antagonists [MoA]
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Narrower (1)
MDL 73,147EF
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Dolasetron mesylate lipidosome injection
王平
2012
Corpus ID: 106375681
本发明涉及一种甲磺酸多拉司琼脂质体注射剂，其中该脂质体注射剂由特定重量配比的甲磺酸多拉司琼、大豆卵磷脂、磷脂酰胆碱、磷脂酰甘油和胆固醇制成。 本发明的脂质体注射剂具有良好的制剂稳定性，长期储存后，脂质体同样保持良好的包封率；本发明提高了制剂产品的质量，增加了药物在体循环中的保留时间，提高了药物的生物利用度，减少了毒副作用，并且制法简单，适合于工业化大生产。
2008
2008
Study on related substances and stability of dolasetron mesylate produced in China
Yang Xiu-li
2008
Corpus ID: 100888048
Objective:To establish an HPLC method for assay the related substances in domestic dolasetron mesylate and to study its stability…
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2006
2006
Health Canada has reminded hospitals that Anzemet [dolasetron] is contraindicated in patients aged < 18 years
2006
Corpus ID: 195123184
2000
2000
[Value of dolasetron mesilate in treatment of postoperative nausea and vomiting].
R. Badaoui
,
A. Yagoubi
,
F. Carpentier
,
M. Riboulot
,
M. Ossart
Presse medicale
2000
Corpus ID: 8412999
1999
1999
Pharmacokinetics of dolasetron with coadministration of cimetidine or rifampin in healthy subjects
D. Dimmitt
,
M. Cramer
,
A. Keung
,
T. Arumugham
,
S. Weir
Cancer Chemotherapy and Pharmacology
1999
Corpus ID: 24562683
Purpose: Dolasetron is a selective 5-HT3 receptor antagonist. The purpose of this study was to determine the effect of cimetidine…
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1999
1999
The Anti-Emetic Efficiacy of Intravenous Dolasetron Mesilate plus Dexamethasone versus Intravenous Dolasetron Mesilate Alone in Patients Receiving Fractionated Chemotherapy
A. Fauser
,
W. Dornoff
,
+4 authors
J. Nowicki
Oncology Research and Treatment
1999
Corpus ID: 58491295
Purpose: Fractionated cisplatin-containing regimens are routinely used for chemotherapy of certain types of cancer. Dolasetron…
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1998
1998
Intravenous Dolasetron Mesilate in the Prevention of Postoperative Nausea and Vomiting in Females Undergoing Gynecological Surgery
P. Diemunsch
,
A. D. Hollander
,
+5 authors
W. Hahne
1998
Corpus ID: 74737440
1998
1998
Dolasetron delivers value in postoperative nausea and vomiting
W. Elwood
1998
Corpus ID: 73215681
Postoperative nausea and vomiting (PONV) has been called the ‘big little problem’ following surgery requiring anaesthesia or…
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1996
1996
A double-blind, randomized, parallel study of IV dolasetron mesilate versus IV metoclopramide in patients receiving moderately emetogenic chemotherapy
A. Fauser
,
H. Bleiberg
,
+8 authors
N. Claverie
1996
Corpus ID: 79409265
Contexte - Cet essai de 24 heures a compare deux doses uniques de mesilate de dolasetron IV (DM) et de metoclopramide (MTC) pour…
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1994
1994
Purification, Reconstitution, and1KBAssociation ofthec-Rel- p65(RelA)Complex, a Strong Activator ofTranscription
Copenhagen K Denmark
,
S. Raffaele
1994
Corpus ID: 82675212
HeLacells contain aDNA-binding activity whichassociates witha KB-like DNA element, termedRel-related protein-binding element…
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