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Digitoxin

Known as: Digitoksin, (3beta,5beta)-3-[(O-2,6-Dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide, Digitoxoside 
A lipid soluble cardiac glycoside that inhibits the plasma membrane sodium potassium ATPase, leading to increased intracellular sodium and calcium… 
National Institutes of Health

Related topics

Related topics

39 relations

Narrower (10)

3'''-diazomalonyldigitoxinCoramedanDigimedDigimerck
AmyloidosisAtrial FibrillationAtrial FlutterCongestive heart failure

Broader (4)

Anti-Arrhythmia AgentsCardiac GlycosidesCardiotonic AgentsEnzyme Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
[Interaction of quinidine and digitoxin in the human (author's transl)].
With a daily maintenance dose of 0.1 mg digitoxin a mean steady state digitoxin serum concentration of 17.0 +/- 3.2 ng/ml was… 
2005
2005
Zur Kenntnis der Ursachen der Kumulierungserscheinungen der Digitalisglykoside
ZusammenfassungDie in einer vorangehenden Arbeit von F. Büchner im Herzmuskel digitalisvergifteter Katzen nachgewiesenen herdf… 
2004
2004
Quantitative analysis of digoxin, 4‴-acetyldigoxin and 4‴-methyldigoxin and their metabolites in bile and urine of rats
SummaryThe metabolism of digoxin (D), 4‴-acetyldigoxin (AD) and 4″-methyldigoxin (MD) was studied in biliary fistula rats by… 
1979
1979
Differential thermal, solubility, and aging studies on various sources of digoxin and digitoxin powder: biopharmaceutical implications.
Unlike most organic compounds, both digoxin and digitoxin melted over a wide temperature range, with the widest range being 88… 
1977
1977
Pharmakokinetik von Digitoxin bei chronischer Niereninsuffizienz*
: Digitoxin concentration, measured by radio-immunoassay, was significantly lower in 51 patients in chronic renal failure (23.2… 
Highly Cited
1970
Highly Cited
1970
The difference in sensitivity to cardiac steriods of (Na+ + K+)‐stimulated ATPase and amino acid transport in the intestinal mucosa of the rat and other species
1. The effect of various cardioactive steroids on the activity of a microsomal (Na+ + K+)‐activated ATPase from rat intestinal… 
1970
1970
The elekctrokinetic surfaces of human cells of lymphoid origin and their ribonuclease susceptibility.
A comparison has been made of the electrophoretic mobilities of human peripheral lymphocytes, peripheral malignant cells from… 
1959
1959
[On splitting and hydroxylation of digitoxin in the rat].
Ratten i.v. eingespritztes Digitoxin erfahrt durch Fermentwirkung eine schrittweise Kurzung der Digitoxosekette, die uber das Bis… 
Review
1957
Review
1957
Acute massive digitoxin poisoning: report of a case and review of the literature.
Excerpt The opportunity to observe myocardial and metabolic responses to massive digitoxin poisoning was recently afforded us by… 
Review
1952
Review
1952
Thrombopenic purpura following use of digitoxin.
Blood dyscrasias are common complications of the use of numerous medicaments. Recently, severe thrombopenic purpura developed in…