Digitoxin

Known as: Digitoksin, (3beta,5beta)-3-[(O-2,6-Dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide, Digitoxoside 
A lipid soluble cardiac glycoside that inhibits the plasma membrane sodium potassium ATPase, leading to increased intracellular sodium and calcium… (More)
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Accumulating preclinical and clinical data suggest that the cardiac drug digitoxin might be used in cancer therapy. Recent… (More)
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Review
2005
Review
2005
Small RNA guides--microRNAs, small interfering RNAs, and repeat-associated small interfering RNAs, 21 to 30 nucleotides in length… (More)
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Highly Cited
2005
Highly Cited
2005
The cardiac glycosides digitoxin (1) and digoxin (3) have been used in cardiac diseases for many years. During this time several… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Global analysis of the genome, transcriptome, and proteome is facilitated by the recent development of tools for large… (More)
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Highly Cited
2001
Highly Cited
2001
Digitoxin induces apoptosis in different human malignant cell lines in vitro. In this paper we investigated if patients taking… (More)
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Highly Cited
2000
Highly Cited
2000
Elevated circulating levels of an endogenous ouabain (EO) have been associated with essential hypertension. To investigate… (More)
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Highly Cited
1999
Highly Cited
1999
The ability of digitalis to block cell proliferation has been well established for some time. Recently, digitalis in non-toxic… (More)
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Highly Cited
1991
Highly Cited
1991
A defined cultivation system was developed for the differentiation of pluripotent embryonic stem cells of the mouse into… (More)
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Highly Cited
1990
Highly Cited
1990
By means of light and electron microscopic immunocytochemistry, we have localized p80-coilin, a specific protein marker for… (More)
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1969
1969
Spironolactone (Aldactone(R)) protects the rat against the production of myocardial necroses and other manifestations of… (More)
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