Diffuse Astrocytoma

Known as: Astrocytoma, Grade II, Grade II Astrocytomas, astrocytoma diffuse 
A low-grade (WHO grade II) astrocytic neoplasm. It is characterized by diffuse infiltration of neighboring central nervous system structures. These… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The WHO 2007 classification of tumors of the CNS distinguishes between diffuse astrocytoma WHO grade II (A IIWHO2007) and… (More)
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Highly Cited
2011
Highly Cited
2011
Mutations in the PTEN, TP53, and RB1 pathways are obligate events in the pathogenesis of human glioblastomas. We induced various… (More)
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Highly Cited
2010
Highly Cited
2010
The current World Health Organization classification recognizes three histological types of grade II low-grade diffuse glioma… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Diffuse infiltrative low-grade gliomas of the cerebral hemispheres in the adult are a group of tumors with distinct… (More)
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Highly Cited
2010
Highly Cited
2010
Malignant gliomas, the deadliest of brain neoplasms, show rampant genetic instability and resistance to genotoxic therapies… (More)
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Highly Cited
2010
Highly Cited
2010
Heterozygous point mutations of isocitrate dehydrogenase (IDH)1 codon 132 are frequent in grade II and III gliomas. Recently, we… (More)
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Highly Cited
2009
Highly Cited
2009
Separation of pilocytic astrocytoma from diffuse astrocytomas frequently poses problems mostly related to small sample size… (More)
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Highly Cited
2009
Highly Cited
2009
One of the most vexing issues in diagnostic neuropathology relates to the distinction of diffuse astrocytomas (and other diffuse… (More)
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Highly Cited
2000
Highly Cited
2000
Diffuse astrocytoma WHO grade II is a well-differentiated, slowly growing tumor that has an inherent tendency to progress to… (More)
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Highly Cited
2000
Highly Cited
2000
Human gliomas express TGF-beta but, so far the expression of downstream mediators has been investigated in only a few cell lines… (More)
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