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Difenoxin hydrochloride

Known as: 4-Piperidinecarboxylic Acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, Monohydrochloride, Isonipecotic Acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, Hydrochloride 
A phenylpiperidine with antidiarrheal activity and active metabolite of diphenoxylate. Difenoxin is chemically related to the narcotic opioid… 
National Institutes of Health

Related topics

Related topics

9 relations
AntidiarrhealsDiarrheaDrug AllergyEnterocolitis, Pseudomembranous

Broader (2)

Organic Chemicalsdifenoxin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Development and Validation of Gas Chromatographic Method for Residual Solvents Determination in Difenoxin Hydrochloride
Residual solvents in pharmaceuticals are termed as organic Volatile Impurities. These are the chemicals that are used in the… 
1979
1979
[Treatment of diarrhea with difenoxin hydrochloride in children (author's transl)].
In an open clinical study symptomatic treatment was given to 93 children aged 16 days to 24 months who suffered from acute… 
1979
1979
[Double-blind study of difenoxin hydrochloride among travellers to tropical countries (author's transl)].
1979
1979
[Double-blind study on the influence of difenoxin hydrochloride on intestinal passage time in healthy volunteers (author's transl)].
The effect on the intestinal passage of 3 X 1 mg difenoxin hydrochloride (Lyspafen) was tested in a randomised double-blind study… 
1979
1979
[Special consideration of clinical and travelling medical criteria (author's transl)].
The pharmacological properties of difenoxin hydrochloride, a meperidine derivative exerting antidiarrheal effect, are presented… 
1976
1976
[Difenoxin hydrochloride; a new antidiarrheal agent; preliminary results of cases of chronic diarrhoea (author's transl)].
1976
1976
[Diphenoxinhydrochloride, a new anti-diarrhea agent].
The new antidiarrheal drug difenoxin hydrochloride is a preparation with a broad range of action; it is suitable for symptomatic… 
1975
1975
A Single-Blind Trial between Difenoxin and Diphenoxylate
The antidiarrhoeal effect of difenoxin hydrochloride versus diphenoxylate was studied in a single-blind trial. The results… 
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