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Dibucaine

Known as: CINCHOCAINE, 2-N-Butoxy-N-(2-diethylaminoethyl)cinchoninamide, 2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide 
A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell… Expand
National Institutes of Health

Related topics

Related topics

31 relations
AllergensAntipruritic Activity [PE]Assay of dibucaine numberDibucaine / POLICRESULEN
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Narrower (10)

CincainDibucaine 0.01 MG/MG Rectal Ointment [Nupercainal]Dixidextracaine-70Factu
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Broader (1)

Local Anesthetics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
From cocaine to ropivacaine: the history of local anesthetic drugs.
In 1850, about three centuries after the conquest of Peru by Pizzaro, the Austrian von Scherzer brought a sufficient quantum of… Expand
Highly Cited
1989
Highly Cited
1989
Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase.
A point mutation in the gene for human serum cholinesterase was identified that changes Asp-70 to Gly in the atypical form of… Expand
Highly Cited
1987
Highly Cited
1987
Local anesthetics and pressure: a comparison of dibucaine binding to lipid monolayers and bilayers.
  • A. Seelig
  • Biochimica et biophysica acta
  • 1987
    • Corpus ID: 13289859
The binding of the local anesthetic dibucaine to monolayers composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine was… Expand
Highly Cited
1985
Highly Cited
1985
A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.
  • B. Coller
  • The Journal of clinical investigation
  • 1985
    • Corpus ID: 23674209
Considerable evidence indicates that the glycoprotein (GP) IIb/IIIa complex on human platelets functions as a receptor for… Expand
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Highly Cited
1984
Highly Cited
1984
Experimental skeletal muscle damage: the nature of the calcium‐activated degenerative processes
  • M. J. JACKSON, D. A. JONES, R. Edwards
  • European journal of clinical investigation
  • 1984
    • Corpus ID: 6777221
Abstract. The role of calcium‐activated degenerative processes in the efflux of enzyme from experimentally damaged mouse muscle… Expand
Highly Cited
1980
Highly Cited
1980
Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.
Ca2+-activated, phospholipid-dependent protein kinase recently found in mammalian tissues (Takai, Y., Kishimoto, A., Iwasa, Y… Expand
Highly Cited
1980
Highly Cited
1980
Calcium control of waveform in isolated flagellar axonemes of chlamydomonas
The effect of Ca(++) on the waveform of reactivated, isolated axonemes of chlamydomonas flagella was investigated. Flagella were… Expand
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Highly Cited
1978
Highly Cited
1978
Polymorphic phase behaviour of cardiolipin as detected by 31P NMR and freeze-fracture techniques. Effects of calcium, dibucaine and chlorpromazine.
1. The influence of Ca2+ on the polymorphic phase behaviour of cardiolipin has been investigated employing 31P NMR and freeze… Expand
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Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… Expand
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Highly Cited
1963
Highly Cited
1963
Genetical studies on a new variant of serum cholinesterase detected by electrophoresis
1. At least four distinct zones with properties of serum cholinesterase (pseudocholinesterase) may be demonstrated by starch gel… Expand
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