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Dibucaine

Known as: CINCHOCAINE, 2-N-Butoxy-N-(2-diethylaminoethyl)cinchoninamide, 2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide 
A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell… 
National Institutes of Health

Related topics

Related topics

31 relations
AllergensAntipruritic Activity [PE]Assay of dibucaine numberDibucaine / POLICRESULEN

Narrower (10)

CincainDibucaine 0.01 MG/MG Rectal Ointment [Nupercainal]Dixidextracaine-70Factu

Broader (1)

Local Anesthetics

Papers overview

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Highly Cited
1989
Highly Cited
1989
Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase.
A point mutation in the gene for human serum cholinesterase was identified that changes Asp-70 to Gly in the atypical form of… 
Highly Cited
1988
Highly Cited
1988
Partitioning of local anesthetics into membranes: surface charge effects monitored by the phospholipid head-group.
Highly Cited
1985
Highly Cited
1985
Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria.
Highly Cited
1981
Highly Cited
1981
Phospholipid-sensitive calcium-dependent protein kinase: inhibition by antipsychotic drugs.
Highly Cited
1980
Highly Cited
1980
Phospholipid turnover as a possible transmembrane signal for protein phosphorylation during human platelet activation by thrombin.
Highly Cited
1977
Highly Cited
1977
Thrombin, collagen and A23187 stimulated endogenous platelet arachidonate metabolism: differential inhibition by PGE1, local anesthetics and a serine-protease inhibitor.
Highly Cited
1975
Highly Cited
1975
Effects of local anesthetics on membrane properties. II. Enhancement of the susceptibility of mammalian cells to agglutination by plant lectins.
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
Highly Cited
1968
Highly Cited
1968
Interactions of La3+ and local anesthetic drugs with mitochondrial Ca++ and Mn++ uptake.
Highly Cited
1963
Highly Cited
1963
Genetical studies on a new variant of serum cholinesterase detected by electrophoresis
1. At least four distinct zones with properties of serum cholinesterase (pseudocholinesterase) may be demonstrated by starch gel… 
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