Dibucaine

Known as: CINCHOCAINE, 2-N-Butoxy-N-(2-diethylaminoethyl)cinchoninamide, 2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide 
A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell… (More)
National Institutes of Health

Related topics

Related topics

26 relations
AllergensAssay of dibucaine numberDibucaine 0.01 MG/MG Topical OintmentDibucaine hydrochloride
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Narrower (8)

Dixidextracaine-70FactuNeovitacainNupercainal
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Broader (1)

Local Anesthetics

Papers overview

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2011
2011
Calpain Activator Dibucaine Induces Platelet Apoptosis
Calcium-dependent calpains are a family of cysteine proteases that have been demonstrated to play key roles in both platelet… (More)
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2000
2000
Membrane effects of trifluoperazine, dibucaine and praziquantel on human erythrocytes.
Trifluoperazine (TFP) is a potent antipsychotic agent, dibucaine (DBC) is a local anaesthetic and praziquantel (PZQ) is a highly… (More)
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2000
2000
Mechanism of dibucaine-induced apoptosis in promyelocytic leukemia cells (HL-60).
Dibucaine, a local anesthetic, inhibited the growth of promyelocytic leukemia cells (HL-60) without inducing arrest of the cell… (More)
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1998
1998
Ca2+-stimulated mitochondrial reactive oxygen species generation and permeability transition are inhibited by dibucaine or Mg2+.
Mitochondrial swelling and membrane protein thiol oxidation associated with mitochondrial permeability transition induced by Ca2… (More)
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1997
1997
Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones.
1. Glutamate receptor activation has been previously shown to result in mitochondrial depolarization and activation of the… (More)
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1997
1997
Induction of apoptotic cell death in a neuroblastoma cell line by dibucaine.
Dibucaine, a local anesthetic known to interact with cell membranes, induced apoptosis in SK-N-MC human neuroblastoma cells in a… (More)
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Highly Cited
1987
Highly Cited
1987
Local anesthetics and pressure: a comparison of dibucaine binding to lipid monolayers and bilayers.
The binding of the local anesthetic dibucaine to monolayers composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine was… (More)
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Highly Cited
1985
Highly Cited
1985
A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.
Considerable evidence indicates that the glycoprotein (GP) IIb/IIIa complex on human platelets functions as a receptor for… (More)
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Highly Cited
1980
Highly Cited
1980
Calcium control of waveform in isolated flagellar axonemes of chlamydomonas
The effect of Ca(++) on the waveform of reactivated, isolated axonemes of chlamydomonas flagella was investigated. Flagella were… (More)
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1980
1980
Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.
Ca2+-activated, phospholipid-dependent protein kinase recently found in mammalian tissues (Takai, Y., Kishimoto, A., Iwasa, Y… (More)
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