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Dibucaine

Known as: CINCHOCAINE, 2-N-Butoxy-N-(2-diethylaminoethyl)cinchoninamide, 2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide 
A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell… 
National Institutes of Health

Related topics

Related topics

31 relations
AllergensAntipruritic Activity [PE]Assay of dibucaine numberDibucaine / POLICRESULEN

Narrower (10)

CincainDibucaine 0.01 MG/MG Rectal Ointment [Nupercainal]Dixidextracaine-70Factu

Broader (1)

Local Anesthetics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1985
1985
Uptake of dibucaine into large unilamellar vesicles in response to a membrane potential.
Local amine anesthetics appear to exert their effects in the charged (protonated) form on the cytoplasmic side of excitable… 
Highly Cited
1985
Highly Cited
1985
Evidence for a role for cellular alkalinization in the cyclic adenosine 3',5'-monophosphate-mediated initiation of motility in bovine caput spermatozoa.
Bicarbonate ion, the local anesthetics procaine and dibucaine, and the ionophores monensin and nigericin have been shown to… 
1980
1980
Interaction of four local anesthetics with phospholipid bilayer membranes: permeability effects and possible mechanisms.
Sodium 22 efflux was measured, at various temperatures, in the presence of different local anesthetics (dibucaine, tetracaine… 
1979
1979
Release characteristics of dibucaine dispersed in konjac gels.
A possible use of konjac gel for sustained release of drugs was examined in a monolithic system containing dibucaine. Dibucaine… 
1979
1979
Specific binding of perhydrohistrionicotoxin to Torpedo acetylcholine receptor.
Torpedo californica postsynaptic membrane fragments were treated with base, which resulted in membranes that were depleted of… 
1978
1978
Structural difference at the active site of dibucaine resistant variant of human plasma cholinesterase.
Human plasma cholinesterase from five different genotypes -- E1U E1U, E1U E1A, E1A E1A, E1U E1S, E1A E1S, and E1U E1U C5+ -- was… 
Highly Cited
1977
Highly Cited
1977
Factors controlling the activities of phosphatidate phosphohydrolase and phosphatidate cytidylyltransferase. The effects of chlorpromazine, demethylimipramine, cinchocaine, norfenfluramine…
1. Microsomal membranes from rat liver were incubated with ATP, CoA, Mg2+, [14C]palmitate, F- and sn-glycerol 3-phosphate in… 
Highly Cited
1975
Highly Cited
1975
Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine…
The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations… 
Highly Cited
1965
Highly Cited
1965
COMPLETE PSEUDOCHOLINESTERASE DEFICIENCY: GENETIC AND IMMUNOLOGIC CHARACTERIZATION.
The plasma enzyme pseudocholinesterase (acylcholine acyl hydrolase) is composed of a series of related glycoproteins that… 
1959
1959
Differential Response of Human Serum Cholinesterase Types to an Inhibitor in Potato
DIFFERENCES in the degree of inhibition of the activity of human serum cholinesterase (pseudocholinesterase) produced in vitro by… 
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