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Dibucaine

Known as: CINCHOCAINE, 2-N-Butoxy-N-(2-diethylaminoethyl)cinchoninamide, 2-Butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide 
A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell… Expand
National Institutes of Health

Related topics

Related topics

31 relations
AllergensAntipruritic Activity [PE]Assay of dibucaine numberDibucaine / POLICRESULEN
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Narrower (10)

CincainDibucaine 0.01 MG/MG Rectal Ointment [Nupercainal]Dixidextracaine-70Factu
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Broader (1)

Local Anesthetics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
From cocaine to ropivacaine: the history of local anesthetic drugs.
In 1850, about three centuries after the conquest of Peru by Pizzaro, the Austrian von Scherzer brought a sufficient quantum of… Expand
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Highly Cited
1998
Highly Cited
1998
Ca2+-stimulated mitochondrial reactive oxygen species generation and permeability transition are inhibited by dibucaine or Mg2+.
Mitochondrial swelling and membrane protein thiol oxidation associated with mitochondrial permeability transition induced by Ca2… Expand
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Highly Cited
1996
Highly Cited
1996
pDelayed‐type hypersensitivity to subcutaneous lidocaine with tolerance to articaine: confirmation by in vivo and in vitro tests
A 43‐year‐old woman suffered from recurrent localized swellings and an eczematous dermatitis starting 1 day after an injection of… Expand
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Highly Cited
1989
Highly Cited
1989
Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase.
A point mutation in the gene for human serum cholinesterase was identified that changes Asp-70 to Gly in the atypical form of… Expand
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Highly Cited
1988
Highly Cited
1988
Spinal anaesthesia for Caesarean section
Wc read with interest the case report on cardiac arrest in quoted as finding that 'dye injected into a peripheral vcin near term… Expand
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Highly Cited
1987
Highly Cited
1987
Local anesthetics and pressure: a comparison of dibucaine binding to lipid monolayers and bilayers.
  • A. Seelig
  • Biochimica et biophysica acta
  • 1987
    • Corpus ID: 13289859
The binding of the local anesthetic dibucaine to monolayers composed of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine was… Expand
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Highly Cited
1985
Highly Cited
1985
A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.
  • B. Coller
  • The Journal of clinical investigation
  • 1985
    • Corpus ID: 23674209
Considerable evidence indicates that the glycoprotein (GP) IIb/IIIa complex on human platelets functions as a receptor for… Expand
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Highly Cited
1985
Highly Cited
1985
Comparison of the vasoactivity of amide and ester local anaesthetics. An intradermal study.
The vascular effects and duration of action of two ester-linked local anaesthetics, procaine and amethocaine, and four amide… Expand
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Highly Cited
1984
Highly Cited
1984
Experimental skeletal muscle damage: the nature of the calcium‐activated degenerative processes
Abstract. The role of calcium‐activated degenerative processes in the efflux of enzyme from experimentally damaged mouse muscle… Expand
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Highly Cited
1980
Highly Cited
1980
Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated, phospholipid-dependent protein kinase.
Ca2+-activated, phospholipid-dependent protein kinase recently found in mammalian tissues (Takai, Y., Kishimoto, A., Iwasa, Y… Expand
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