Skip to search formSkip to main contentSkip to account menu

Dianhydrogalactitol

Known as: Dulcitol diepoxide, 1,2:5,6 dianhydrogalactitol, 1,2,5,6-Dianhydrogalactitol 
A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (2)

Antineoplastic Agents, AlkylatingGalactitol
In BloodNCIt Antineoplastic Agent Terminologyagonistsanalogs & derivatives

Narrower (2)

NSC-132313dianhydro-3,4-diacetylgalactitol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Lipid rafts, endoplasmic reticulum and mitochondria in the antitumor action of the alkylphospholipid analog edelfosine.
The so-called alkylphospholipid analogs (APLs) constitute a family of synthetic antitumor compounds that target cell membranes… 
Highly Cited
2005
Highly Cited
2005
Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells Cultured onto Three Different Polymers In Vitro
In this study, the osteoinductive and cell-binding properties of three different resorbable polymers were evaluated by human… 
2003
2003
Desymmetrization of a centrosymmetric diepoxide: efficient synthesis of a key intermediate in a total synthesis of hemibrevetoxin B.
The preparation of an established intermediate in a total synthesis of hemibrevetoxin B is described. The acid-catalyzed… 
Highly Cited
2001
Highly Cited
2001
Expression and Redistribution of Cellular Bad, Bax, and Bcl-xL Protein Is Associated with VCD-Induced Ovotoxicity in Rats1
Abstract Previous studies have shown that 4-vinylcyclohexene diepoxide (VCD)-induced ovotoxicity in rats is likely caused by… 
2001
2001
First Desymmetrization of a Centrosymmetric Molecule in Natural Product Synthesis: Preparation of a Key Fragment in the Synthesis of Hemibrevetoxin B.
Exploitation of molecular symmetry can greatly improve the efficiency of syntheses. The symmetry embedded in the centrosymmetric… 
Highly Cited
1999
Highly Cited
1999
A single dose of the ovotoxicant 4-vinylcyclohexene diepoxide is protective in rat primary ovarian follicles.
Repeated dosing of rats with the ovotoxic chemical, 4-vinylcyclohexene diepoxide (VCD), destroys primordial and primary ovarian… 
1991
1991
Studies on the reactivity of acyl glucuronides--I. Phenolic glucuronidation of isomers of diflunisal acyl glucuronide in the rat.
1991
1991
Thrombin induces a biphasic 1,2-diacylglycerol production in human platelets.
The 1,2-diacylglycerol (DAG) mass content was measured in thrombin-stimulated human platelets. Thrombin stimulates a biphasic… 
1989
1989
Dynamics of the diradylglycerol responses of stimulated phagocytes.
Highly Cited
1977
Highly Cited
1977
Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)