Dianhydrogalactitol

Known as: Dulcitol diepoxide, 1,2:5,6 dianhydrogalactitol, 1,2,5,6-Dianhydrogalactitol 
A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group… (More)
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Antineoplastic Agents, AlkylatingGalactitol
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Narrower (2)

NSC-132313dianhydro-3,4-diacetylgalactitol

Papers overview

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2007
2007
Lipids of human meibum: mass-spectrometric analysis and structural elucidation.
The purpose of this study was to structurally characterize the major lipid species present in human meibomian gland secretions… (More)
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2007
2007
A possible cellular explanation for the NMR-visible mobile lipid (ML) changes in cultured C6 glioma cells with growth.
The NMR-visible mobile lipid (ML) signals of C6 glioma cells have been monitored at 9.4 and 11.7 T (single pulse and 136 ms echo… (More)
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2006
2006
Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice.
Genetic and biochemical analyses have uncovered an essential role for nuclear factor erythroid 2-related factor 2 (Nrf2) in… (More)
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2005
2005
Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells Cultured onto Three Different Polymers In Vitro
In this study, the osteoinductive and cell-binding properties of three different resorbable polymers were evaluated by human… (More)
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Highly Cited
2004
Highly Cited
2004
The follicle-deplete mouse ovary produces androgen.
The follicle-depleted postmenopausal ovary is enriched in interstitial cells that produce androgens. This study was designed to… (More)
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2004
2004
Ceramide in the antiapoptotic effect of ischemic preconditioning.
Although the mechanism by which ischemic preconditioning (PC) inhibits myocardial apoptosis during ischemia-reperfusion is… (More)
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1999
1999
Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats - effects of feeding.
The mechanisms of insulin resistance in the obese Zucker rat have not been clearly established but increased diacylglycerol… (More)
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1996
1996
Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats.
Previous studies have determined that 4-vinylcyclohexene diepoxide (VCD) causes specific destruction of oocytes contained in… (More)
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1996
1996
The effect of ionizing radiation on signal transduction: antibodies to EGF receptor sensitize A431 cells to radiation.
What determines the degree of cell-resistance or sensitivity to ionizing radiation is not yet known. As a corollary to the… (More)
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Highly Cited
1989
Highly Cited
1989
Testing for increased carcinogenicity using a survival-adjusted quantal response test.
The linear trend test in proportions is frequently used to analyze the results of animal carcinogenicity experiments. This test… (More)
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