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Dianhydrogalactitol

Known as: Dulcitol diepoxide, 1,2:5,6 dianhydrogalactitol, 1,2,5,6-Dianhydrogalactitol 
A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (2)

Antineoplastic Agents, AlkylatingGalactitol
In BloodNCIt Antineoplastic Agent Terminologyagonistsanalogs & derivatives

Narrower (2)

NSC-132313dianhydro-3,4-diacetylgalactitol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Lipid rafts, endoplasmic reticulum and mitochondria in the antitumor action of the alkylphospholipid analog edelfosine.
The so-called alkylphospholipid analogs (APLs) constitute a family of synthetic antitumor compounds that target cell membranes… 
Highly Cited
2007
Highly Cited
2007
A possible cellular explanation for the NMR-visible mobile lipid (ML) changes in cultured C6 glioma cells with growth.
Highly Cited
2005
Highly Cited
2005
Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells Cultured onto Three Different Polymers In Vitro
In this study, the osteoinductive and cell-binding properties of three different resorbable polymers were evaluated by human… 
2003
2003
Desymmetrization of a centrosymmetric diepoxide: efficient synthesis of a key intermediate in a total synthesis of hemibrevetoxin B.
The preparation of an established intermediate in a total synthesis of hemibrevetoxin B is described. The acid-catalyzed… 
2003
2003
Testing Recursive Path Models With Correlated Errors Using D-Separation
This article shows how to extend the inferential test of Shipley (2000b), which is applicable to recursive path models without… 
Highly Cited
2001
Highly Cited
2001
Expression and Redistribution of Cellular Bad, Bax, and Bcl-xL Protein Is Associated with VCD-Induced Ovotoxicity in Rats1
Abstract Previous studies have shown that 4-vinylcyclohexene diepoxide (VCD)-induced ovotoxicity in rats is likely caused by… 
Highly Cited
1999
Highly Cited
1999
A single dose of the ovotoxicant 4-vinylcyclohexene diepoxide is protective in rat primary ovarian follicles.
Repeated dosing of rats with the ovotoxic chemical, 4-vinylcyclohexene diepoxide (VCD), destroys primordial and primary ovarian… 
1989
1989
Dynamics of the diradylglycerol responses of stimulated phagocytes.
Review
1978
Review
1978
Patterns of resistance and therapeutic synergism among alkylating agents.
Alkylating anticancer drugs are varied in chemical structure, alkylating moieties, and likely mechanisms of cytotoxic activity… 
Highly Cited
1977
Highly Cited
1977
Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The… 
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