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Dianhydrogalactitol

Known as: Dulcitol diepoxide, 1,2:5,6 dianhydrogalactitol, 1,2,5,6-Dianhydrogalactitol 
A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group… 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
The so-called alkylphospholipid analogs (APLs) constitute a family of synthetic antitumor compounds that target cell membranes… 
Highly Cited
2005
Highly Cited
2005
In this study, the osteoinductive and cell-binding properties of three different resorbable polymers were evaluated by human… 
2003
2003
The preparation of an established intermediate in a total synthesis of hemibrevetoxin B is described. The acid-catalyzed… 
Highly Cited
2001
Highly Cited
2001
Abstract Previous studies have shown that 4-vinylcyclohexene diepoxide (VCD)-induced ovotoxicity in rats is likely caused by… 
2001
2001
Exploitation of molecular symmetry can greatly improve the efficiency of syntheses. The symmetry embedded in the centrosymmetric… 
Highly Cited
1999
Highly Cited
1999
Repeated dosing of rats with the ovotoxic chemical, 4-vinylcyclohexene diepoxide (VCD), destroys primordial and primary ovarian… 
1991
1991
The 1,2-diacylglycerol (DAG) mass content was measured in thrombin-stimulated human platelets. Thrombin stimulates a biphasic… 
Highly Cited
1977
Highly Cited
1977
Single agents and combinations of agents were tested for antitumor activity against four transplantable colon tumors in mice. The…