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Contrast-induced acute kidney injury is an important clinical event with a worldwide increasing number of cases. Medullary… Expand Descending vasa recta (DVR) are 12- to 15-μm microvessels that supply the renal medulla with blood flow. We examined the ability… Expand PURPOSE
To determine whether a type of contrast medium (CM), iodixanol, modifies outer medullary descending vasa recta (DVR… Expand The manner in which vasa recta function and contribute to the concentrating mechanism depends on their three-dimensional… Expand Strong inward rectifier potassium channels are expressed by some vascular smooth muscle cells and facilitate K+-induced… Expand The PDZ domain adaptor protein Na+/H+ exchanger regulatory factor (NHERF)-2 is expressed in renal medullary descending vasa recta… Expand We tested whether chronic ANG II infusion into rats affects descending vasa recta (DVR) contractility, synthesis of superoxide… Expand We tested whether luminal perfusion and pressurization induce an endothelial cytoplasmic Ca(2+) ([Ca(2+)](CYT)) response in… Expand In this model of oxygen transport in the renal medullary microcirculation, we predicted that the net amount of oxygen reabsorbed… Expand We tested the hypothesis that constriction of descending vasa recta (DVR) is mediated by voltage-gated calcium entry. K… Expand