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DepoCyt

Known as: Depo-Cyt, DepoFoam Encapsulated Cytarabine 
National Institutes of Health

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2 relations
CytarabineCytarabine liposome

Papers overview

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Review
2019
Review
2019
Vesicular phospholipid gels as drug delivery systems for small molecular weight drugs, peptides and proteins: State of the art review.
2013
2013
Improving patient outcomes through advanced pain management techniques in total hip and knee arthroplasty.
Pain following orthopedic surgery is common and often suboptimally managed, with many patients reporting acute moderate to severe… 
Highly Cited
2012
Highly Cited
2012
Neurotoxicity of intra-CSF liposomal cytarabine (DepoCyt) administered for the treatment of leptomeningeal metastases: a retrospective case series
Treatment of leptomeningeal metastasis (LMD) remains challenging due to advanced systemic disease at presentation and limited… 
Highly Cited
2006
Highly Cited
2006
A pharmacokinetic study of intra-CSF administered encapsulated cytarabine (DepoCyt®) for the treatment of neoplastic meningitis in patients with leukemia, lymphoma, or solid tumors as part of a phase…
SummaryIntroductionCytarabine liposome injection (DepoCyt®), a sterile suspension of the antimetabolite cytarabine, encapsulated… 
Review
2006
Review
2006
Pharmacology of Drugs Formulated with DepoFoam™
Lamellar liposome technology has been used for several decades to produce sustained-release drug formulations for parenteral… 
Highly Cited
2004
Highly Cited
2004
An Open Label Trial of Sustained-release Cytarabine (DepoCyt™) for the Intrathecal Treatment of Solid Tumor Neoplastic Meningitis
Drugs currently available for intrathecal administration are cleared rapidly from the CSF. DepoCyt is a slow-release formulation… 
2003
2003
Drug delivery systems in cancer therapy
Part I: Pharmacological Considerations for Drug Delivery Systems in Cancer Medicine Systemically Administered Drugs Reginald B… 
Review
2000
Review
2000
Clinical Pharmacology of Encapsulated Sustained-Release Cytarabine
BACKGROUND: The therapeutic effectiveness of chemotherapy is often limited by the inability to sustain cytotoxic concentrations… 
Highly Cited
1999
Highly Cited
1999
A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors.
Standard treatment for neoplastic meningitis requires frequent intrathecal (IT) injections of chemotherapy and is only modestly… 
Highly Cited
1999
Highly Cited
1999
Randomized trial of a slow-release versus a standard formulation of cytarabine for the intrathecal treatment of lymphomatous meningitis.
PURPOSE To evaluate the efficacy and safety of a slow-release formulation of cytarabine (DepoCyt; Chiron Corp, Emeryville, CA… 
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