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Demyelination
Known as:
Demyelinations
, Dysmyelination
, myelinolysis
Breakdown, or abnormal development, of a nerve fiber myelin sheath.
National Institutes of Health
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Related topics
Related topics
24 relations
Abetalipoproteinemia
Balo's Concentric Sclerosis
CDISC SEND Non-Neoplastic Finding Type Terminology
Central Nervous System Signs and Symptoms
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Narrower (6)
Demyelinating Diseases
Encephalomyelitis, Acute Disseminated
Myelinolysis, Central Pontine
Neuromyelitis Optica
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Broader (1)
nervous system disorder
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
V. Cappello
,
L. Marchetti
,
+5 authors
M. Gemmi
Scientific reports
2016
Corpus ID: 38593295
Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by…
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Highly Cited
2011
Highly Cited
2011
Inflammatory cortical demyelination in early multiple sclerosis.
C. Lucchinetti
,
B. Popescu
,
+10 authors
R. Ransohoff
The New England journal of medicine
2011
Corpus ID: 8691519
BACKGROUND Cortical disease has emerged as a critical aspect of the pathogenesis of multiple sclerosis, being associated with…
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Highly Cited
2011
Highly Cited
2011
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
K. Berer
,
M. Mues
,
+5 authors
G. Krishnamoorthy
Nature
2011
Corpus ID: 12678288
Active multiple sclerosis lesions show inflammatory changes suggestive of a combined attack by autoreactive T and B lymphocytes…
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Highly Cited
2005
Highly Cited
2005
Cortical demyelination and diffuse white matter injury in multiple sclerosis.
A. Kutzelnigg
,
C. Lucchinetti
,
+6 authors
H. Lassmann
Brain : a journal of neurology
2005
Corpus ID: 17498094
Focal demyelinated plaques in white matter, which are the hallmark of multiple sclerosis pathology, only partially explain the…
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Highly Cited
2002
Highly Cited
2002
Dysmyelination Revealed through MRI as Increased Radial (but Unchanged Axial) Diffusion of Water
Sheng-Kwei Song
,
Shu-wei Sun
,
M. Ramsbottom
,
Chen Chang
,
J. Russell
,
A. Cross
NeuroImage
2002
Corpus ID: 43229972
Myelin loss and axonal damage are both observed in white matter injuries. Each may have significant impact on the long-term…
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Review
2001
Review
2001
The Neurotoxicant, Cuprizone, as a Model to Study Demyelination and Remyelination in the Central Nervous System
G. Matsushima
,
P. Morell
Brain pathology
2001
Corpus ID: 12796606
Myelin of the adult CNS is vulnerable to a variety of metabolic, toxic, and autoimmune insults. That remyelination can ensue…
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Highly Cited
2000
Highly Cited
2000
Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
C. Lucchinetti
,
W. Brück
,
J. Parisi
,
B. Scheithauer
,
Moses Rodriguez
,
H. Lassmann
Annals of neurology
2000
Corpus ID: 14630021
Multiple sclerosis (MS) is a disease with profound heterogeneity in clinical course, neuroradiological appearance of the lesions…
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Highly Cited
2000
Highly Cited
2000
Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation.
A. Bitsch
,
J. Schuchardt
,
S. Bunkowski
,
T. Kuhlmann
,
W. Brück
Brain : a journal of neurology
2000
Corpus ID: 21244919
Damage to axons is taken as a key factor of disability in multiple sclerosis, but its pathogenesis is largely unknown. Axonal…
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Review
1986
Review
1986
Osmotic demyelination syndrome following correction of hyponatremia.
R. Sterns
,
J. Riggs
,
S. Schochet
The New England journal of medicine
1986
Corpus ID: 46257173
The treatment of hyponatremia is controversial: some authorities have cautioned that rapid correction causes central pontine…
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Highly Cited
1975
Highly Cited
1975
Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination
H. Lipton
Infection and immunity
1975
Corpus ID: 20906771
An unusual biphasic central nervous system disease developed in 3-week-old Swiss outbred mice after intracerebral inoculation of…
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