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Demyelination

Known as: Demyelinations, Dysmyelination, myelinolysis 
Breakdown, or abnormal development, of a nerve fiber myelin sheath.
National Institutes of Health

Related topics

Related topics

24 relations
AbetalipoproteinemiaBalo's Concentric SclerosisCDISC SEND Non-Neoplastic Finding Type TerminologyCentral Nervous System Signs and Symptoms
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Narrower (6)

Demyelinating DiseasesEncephalomyelitis, Acute DisseminatedMyelinolysis, Central PontineNeuromyelitis Optica
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Broader (1)

nervous system disorder

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by… 
Highly Cited
2011
Highly Cited
2011
Inflammatory cortical demyelination in early multiple sclerosis.
BACKGROUND Cortical disease has emerged as a critical aspect of the pathogenesis of multiple sclerosis, being associated with… 
Highly Cited
2011
Highly Cited
2011
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
Active multiple sclerosis lesions show inflammatory changes suggestive of a combined attack by autoreactive T and B lymphocytes… 
Highly Cited
2005
Highly Cited
2005
Cortical demyelination and diffuse white matter injury in multiple sclerosis.
Focal demyelinated plaques in white matter, which are the hallmark of multiple sclerosis pathology, only partially explain the… 
Highly Cited
2002
Highly Cited
2002
Dysmyelination Revealed through MRI as Increased Radial (but Unchanged Axial) Diffusion of Water
Myelin loss and axonal damage are both observed in white matter injuries. Each may have significant impact on the long-term… 
Review
2001
Review
2001
The Neurotoxicant, Cuprizone, as a Model to Study Demyelination and Remyelination in the Central Nervous System
Myelin of the adult CNS is vulnerable to a variety of metabolic, toxic, and autoimmune insults. That remyelination can ensue… 
Highly Cited
2000
Highly Cited
2000
Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
Multiple sclerosis (MS) is a disease with profound heterogeneity in clinical course, neuroradiological appearance of the lesions… 
Highly Cited
2000
Highly Cited
2000
Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation.
Damage to axons is taken as a key factor of disability in multiple sclerosis, but its pathogenesis is largely unknown. Axonal… 
Review
1986
Review
1986
Osmotic demyelination syndrome following correction of hyponatremia.
The treatment of hyponatremia is controversial: some authorities have cautioned that rapid correction causes central pontine… 
Highly Cited
1975
Highly Cited
1975
Theiler's virus infection in mice: an unusual biphasic disease process leading to demyelination
  • H. Lipton
  • Infection and immunity
  • 1975
  • Corpus ID: 20906771
An unusual biphasic central nervous system disease developed in 3-week-old Swiss outbred mice after intracerebral inoculation of… 
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