Demyelination

Known as: Demyelinations, Dysmyelination, myelinolysis 
Breakdown, or abnormal development, of a nerve fiber myelin sheath.
National Institutes of Health

Related topics

Related topics

23 relations
AbetalipoproteinemiaBalo's Concentric SclerosisCDISC SEND Non-Neoplastic Finding Type TerminologyCentral Nervous System Signs and Symptoms
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Narrower (6)

Demyelinating DiseasesEncephalomyelitis, Acute DisseminatedMyelinolysis, Central PontineNeuromyelitis Optica
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Broader (1)

nervous system disorder

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Matrix metalloproteinases in the brain and blood-brain barrier: Versatile breakers and makers.
Matrix metalloproteinases are versatile endopeptidases with many different functions in the body in health and disease. In the… (More)
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Highly Cited
2011
Highly Cited
2011
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
Active multiple sclerosis lesions show inflammatory changes suggestive of a combined attack by autoreactive T and B lymphocytes… (More)
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Highly Cited
2011
Highly Cited
2011
Quantification of increased cellularity during inflammatory demyelination.
Multiple sclerosis is characterized by inflammatory demyelination and irreversible axonal injury leading to permanent… (More)
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Highly Cited
2011
Highly Cited
2011
Radial diffusivity predicts demyelination in <ce:italic>ex vivo</ce:italic> multiple sclerosis spinal cords
OBJECTIVE Correlation of diffusion tensor imaging (DTI) with histochemical staining for demyelination and axonal damage in… (More)
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Highly Cited
2010
Highly Cited
2010
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.
After central nervous system (CNS) demyelination-such as occurs during multiple sclerosis-there is often spontaneous regeneration… (More)
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Highly Cited
2007
Highly Cited
2007
Extensive hippocampal demyelination in multiple sclerosis.
Memory impairment is especially prominent within the spectrum of cognitive deficits in multiple sclerosis (MS), and a crucial… (More)
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Highly Cited
2005
Highly Cited
2005
Cortical demyelination and diffuse white matter injury in multiple sclerosis.
Focal demyelinated plaques in white matter, which are the hallmark of multiple sclerosis pathology, only partially explain the… (More)
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Highly Cited
2000
Highly Cited
2000
Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination.
Multiple sclerosis (MS) is a disease with profound heterogeneity in clinical course, neuroradiological appearance of the lesions… (More)
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Highly Cited
2000
Highly Cited
2000
Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation.
Damage to axons is taken as a key factor of disability in multiple sclerosis, but its pathogenesis is largely unknown. Axonal… (More)
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Review
1994
Review
1994
Multiple sclerosis
Differences in the risk of multiple sclerosis depending on racial background, and the high clinical concordance rates in… (More)
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