Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Abetalipoproteinemia

Known as: Acanthocytosis, MTP DEFICIENCY, Microsomal Triglyceride Transfer Protein Deficiency Disease 
An autosomal recessive disorder of lipid metabolism. It is caused by mutation of the microsomal triglyceride transfer protein that catalyzes the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Abstract Following high-profile government and industry studies, electric aircraft propulsion has emerged as an important… Expand
  • figure 1
  • figure 2
  • table 3
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The Bcr-Abl tyrosine kinase oncogene causes chronic myelogenous leukemia (CML) and Philadelphia chromosome-positive (Ph+) acute… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2005
Review
2005
  • R. Ren
  • Nature Reviews Cancer
  • 2005
  • Corpus ID: 42088783
Imatinib, a potent inhibitor of the oncogenic tyrosine kinase BCR–ABL, has shown remarkable clinical activity in patients with… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Resistance to the ABL kinase inhibitor imatinib (STI571 or Gleevec) in chronic myeloid leukemia (CML) occurs through selection… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Through sequencing analysis of blood or bone marrow samples from patients with chronic myeloid leukemia, we identified BCR-ABL… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Selective inhibition of the BCR-ABL tyrosine kinase by imatinib (STI571, Glivec/Gleevec) is a promising new therapeutic strategy… Expand
  • table 1
  • table 2
  • table 4
  • figure 2
  • figure 1
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The inadvertent fusion of the bcr gene with the abl gene results in a constitutively active tyrosine kinase (Bcr-Abl) that… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Review
2000
Review
2000
Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph… Expand
  • figure 1
  • figure 3
  • figure 2
  • table 1
  • figure 4
Is this relevant?
Review
2000
Review
2000
The microsomal triglyceride transfer protein (MTP) is a dimeric lipid transfer protein consisting of protein disulfide isomerase… Expand
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Abetalipoproteinemia is a human genetic disease that is characterized by a defect in the assembly or secretion of plasma very low… Expand
Is this relevant?